672-87-7
672-87-7
Chemical Structure
Metyrosine
- CAS No.: 672-87-7
- Formula:C10H13NO3
- Molecular Weight:195.22
IUPAC Name: (S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid
InChIKey: NHTGHBARYWONDQ-JTQLQIEISA-N
SMILES: C[C@](C(O)=O)(N)CC1=CC=C(O)C=C1
Biological Activity: Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. Metyrosine significantly inhibits high COX-2 activity[1]. Metyrosine is a very effective agent for blood pressure control[2].
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Metyrosine | 99.29% | Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. Metyrosine significantly inhibits high COX-2 activity. Metyrosine is a very effective agent for blood pressure control. | ||||||||||||||||||||
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Metyrosine (Standard) | ≥98% | Metyrosine (Standard) is the analytical standard of Metyrosine. This product is intended for research and analytical applications. Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. Metyrosine significantly inhibits high COX-2 activity. Metyrosine is a very effective agent for blood pressure control. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-33549RRacemetirosine (Standard) -
Similarity Score 0.89
HY-178277SL-Tyrosine-d1 -
Similarity Score 0.86
HY-121809DL-Methyldopa -
Similarity Score 0.86
HY-B0225Methyldopa -
Similarity Score 0.86
HY-W387035D-α-Methyl DOPA -
Similarity Score 0.85
HY-W016552(S)-2-Amino-2-methyl-3-phenylpropanoic acid -
Similarity Score 0.85
HY-W141831α-Methyl-DL-phenylalanine -
Similarity Score 0.83
HY-N0473S1L-Tyrosine-15N -
Similarity Score 0.83
HY-N0473S4L-Tyrosine-13C -
Explore the MedChemAI to find more analogs
References
- [1]. Albayrak A, Polat B, Cadirci E, et al. Gastric anti-ulcerative and anti-inflammatory activity of metyrosine in rats. Pharmacol Rep. 2010;62(1):113‐119. [Content Brief]
- [2]. Garg MK, et al. Medical management of pheochromocytoma: Role of the endocrinologist. Indian J Endocrinol Metab. 2011;15 Suppl 4(Suppl4):S329‐S336. [Content Brief]
