714240-31-0
714240-31-0
Chemical Structure
NCGC00029283
- CAS No.: 714240-31-0
- Formula:C18H12FN3O3
- Molecular Weight:337.30
IUPAC Name: 3-(5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl)-6-methoxyquinolin-2(1H)-one
InChIKey: FJQADEHMIMENRE-UHFFFAOYSA-N
SMILES: O=C1NC2=C(C=C(OC)C=C2)C=C1C3=NOC(C4=CC=C(F)C=C4)=N3
Biological Activity: NCGC00029283 is a werner syndrome helicase-nuclease (WRN) helicase inhibitor with IC50s of 2.3 μM, 12.5 μM, and 3.4 μM for WRN, BLM and FANCJ helicase, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NCGC00029283 | 98.88% | NCGC00029283 is a werner syndrome helicase-nuclease (WRN) helicase inhibitor with IC50s of 2.3 μM, 12.5 μM, and 3.4 μM for WRN, BLM and FANCJ helicase, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.84
HY-182634NCGC00063279 -
Similarity Score 0.62
HY-128439BT173 -
Similarity Score 0.60
HY-106025Radequinil -
Similarity Score 0.59
HY-141648Antibacterial agent 219 -
Similarity Score 0.56
HY-179050Androgen receptor-IN-7 -
Similarity Score 0.53
HY-146259hCAIX/XII-IN-4 -
Similarity Score 0.53
HY-181408Steroid sulfatase-IN-11 -
Similarity Score 0.52
HY-161982JNU-0921 -
Similarity Score 0.52
HY-144634DDO-7263 -
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