NCGC00029283
Based on 1 Customer Validation
NCGC00029283 is a werner syndrome helicase-nuclease (WRN) helicase inhibitor with IC50s of 2.3 μM, 12.5 μM, and 3.4 μM for WRN, BLM and FANCJ helicase, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.88%
- CAS 番号: 714240-31-0
- 分子式: C18H12FN3O3
- 分子量:337.30
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
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Helicase |
NCGC00029283 (0-100 μM; 24-72 h) effectively blocks cell proliferation in U2-OS cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:U2-OS cells
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Concentration:1 μM, 10 μM, 100 μM
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Incubation Time:24 h, 48 h, 72 h
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Result:Showed a reduction in U2-OS cell proliferation.
化学情報
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CAS 番号 714240-31-0
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性状 Solid
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分子量 337.30
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分子式 C18H12FN3O3
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Color White to yellow
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SMILES
O=C1NC2=C(C=C(OC)C=C2)C=C1C3=NOC(C4=CC=C(F)C=C4)=N3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 6.94 mg/mL (20.58 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (393 KB)
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- Français - FR (393 KB)
- Deutsch - DE (393 KB)
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- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9647 mL | 14.8236 mL | 29.6472 mL | 74.1180 mL |
| 5 mM | 0.5929 mL | 2.9647 mL | 5.9294 mL | 14.8236 mL | |
| 10 mM | 0.2965 mL | 1.4824 mL | 2.9647 mL | 7.4118 mL | |
| 15 mM | 0.1976 mL | 0.9882 mL | 1.9765 mL | 4.9412 mL | |
| 20 mM | 0.1482 mL | 0.7412 mL | 1.4824 mL | 3.7059 mL |
NCGC00029283 関連分類
HY-128712 関連分類
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