72822-13-0
72822-13-0
Chemical Structure
Dapiprazole hydrochloride
- CAS No.: 72822-13-0
- Formula:C19H28ClN5
- Molecular Weight:361.91
IUPAC Name: 3-(2-(4-(o-tolyl)piperazin-1-yl)ethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine hydrochloride
InChIKey: ZIODNPFQZIHCOE-UHFFFAOYSA-N
SMILES: CC1=CC=CC=C1N2CCN(CCC3=NN=C4CCCCN43)CC2.[H]Cl
Biological Activity: Dapiprazole hydrochloride is a potent, selective and orally active alpha-1 adrenoceptor antagonist. Dapiprazole hydrochloride suppresses the opioid withdrawal symptoms. Dapiprazole hydrochloride is also used as eye drops for reversing mydriasis[1][2][3].
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Dapiprazole hydrochloride | 99.26% | Dapiprazole hydrochloride is a potent, selective and orally active alpha-1 adrenoceptor antagonist. Dapiprazole hydrochloride suppresses the opioid withdrawal symptoms. Dapiprazole hydrochloride is also used as eye drops for reversing mydriasis. | ||||||||||||||||||||
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Dapiprazole hydrochloride (Standard) | ≥98% | Dapiprazole (hydrochloride) (Standard) is the analytical standard of Dapiprazole (hydrochloride). This product is intended for research and analytical applications. Dapiprazole hydrochloride is a potent, selective and orally active alpha-1 adrenoceptor antagonist. Dapiprazole hydrochloride suppresses the opioid withdrawal symptoms. Dapiprazole hydrochloride is also used as eye drops for reversing mydriasis. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-A0142Dapiprazole -
Similarity Score 0.54
HY-123368Zolertine hydrochloride -
Similarity Score 0.54
HY-183177Zolertine -
Similarity Score 0.52
HY-106753Tolnapersine -
Similarity Score 0.51
HY-124686ER-464195-01 -
Similarity Score 0.50
HY-106690Centhaquin -
Similarity Score 0.50
HY-160038GAC0003A4 -
Similarity Score 0.49
HY-21098PD-168077 -
Similarity Score 0.49
HY-124501LY 165163 -
Explore the MedChemAI to find more analogs
References
- [1]. Valeri P, et al. Effects of dapiprazole, clonidine and yohimbine on the development of dependence and withdrawal behaviour in mice. Drug Alcohol Depend. 1989 Jan;23(1):73-7. [Content Brief]
- [2]. Allinson RW, et al. Reversal of mydriasis by dapiprazole. Ann Ophthalmol. 1990 Apr;22(4):131-3, 138. [Content Brief]
- [3]. Hou RH, et al. Arousal and the pupil: why diazepam-induced sedation is not accompanied by miosis. Psychopharmacology (Berl). 2007 Nov;195(1):41-59. [Content Brief]
