748159-43-5
748159-43-5
Chemical Structure
(S)-HDAC-IN-102
- CAS 番号: 748159-43-5
- Formula:C18H28O4
- Molecular Weight:308.41
InChIKey: FBIPGCRLBUAKTF-INIZCTEOSA-N
SMILES: CCCCC[C@H](OC)CC(CCC1=CC(OC)=C(C=C1)O)=O
Biological Activity: (S)-HDAC-IN-102 is a HDAC8 inhibitor and an isomer of HDAC-IN-102 (HY-185554). HDAC-IN-102 inhibits total HDAC with an IC50 of 58 μM and exhibits partial subtype selectivity. Specifically, (S)-HDAC-IN-102 targets HDAC8, while (R)-HDAC-IN-102 (HY-185554B) targets HDAC2. HDAC-IN-102 exerts antioxidant effects by scavenging DPPH free radicals and can be used in cancer-related research[1].
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(S)-HDAC-IN-102 | (S)-HDAC-IN-102 is a HDAC8 inhibitor and an isomer of HDAC-IN-102 (HY-185554). HDAC-IN-102 inhibits total HDAC with an IC50 of 58 μM and exhibits partial subtype selectivity. Specifically, (S)-HDAC-IN-102 targets HDAC8, while (R)-HDAC-IN-102 (HY-185554B) targets HDAC2. HDAC-IN-102 exerts antioxidant effects by scavenging DPPH free radicals and can be used in cancer-related research. | |||||||||||||||||||||
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References
Keywords
