804-30-8
804-30-8
Chemical Structure
Fursultiamine
- CAS No.: 804-30-8
- Formula:C17H26N4O3S2
- Molecular Weight:398.54
IUPAC Name: (E)-N-((4-amino-2-methylpyrimidin-5-yl)methyl)-N-(5-hydroxy-3-(((tetrahydrofuran-2-yl)methyl)disulfanyl)pent-2-en-2-yl)formamide
InChIKey: JTLXCMOFVBXEKD-FOWTUZBSSA-N
SMILES: O=CN(CC1=CN=C(C)N=C1N)/C(C)=C(SSCC2OCCC2)\CCO
Biological Activity: Fursultiamine is a vitamin B1 derivative, has anti-nociceptive and antineoplastic activity. Fursultiamine can be used for vitamin B1?deficiency, osteoarthritis (OA) and cancer research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fursultiamine | 99.71% | Fursultiamine is a vitamin B1 derivative, has anti-nociceptive and antineoplastic activity. Fursultiamine can be used for vitamin B1?deficiency, osteoarthritis (OA) and cancer research. | ||||||||||||||||||||
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Fursultiamine (Standard) | ≥98% | Fursultiamine (Standard) is the analytical standard of Fursultiamine. This product is intended for research and analytical applications. Fursultiamine is a vitamin B1 derivative, has anti-nociceptive and antineoplastic activity. Fursultiamine can be used for vitamin B1 deficiency, osteoarthritis (OA) and cancer research. | ||||||||||||||||||||
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Octotiamine | Octotiamine (TATD) is a vitamin B1 analogue, a component of vitamin complex. Octotiamine can be used for the research of vitamin B1 deficiency. | |||||||||||||||||||||
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Prosultiamine | Prosultiamine is an allithiamine homolog. Prosultiamine can disrupt intracellular redox reactions, inducing caspase-dependent apoptosis in HTLV-1 infected cells. Prosultiamine can be used in studies involving lower urinary tract dysfunction associated with human T-lymphotropic virus type 1-related myelopathy/tropical spastic paraparesis. |
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Acefurtiamine | Acefurtiamine is a vitamin B1 analogue. | |||||||||||||||||||||
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Benfotiamine | 99.38% | Benfotiamine (S-Benzoylthiamine O-monophosphate) is a vitamin B1 derivative that exhihibits potent antioxidative and anti-inflammatory activity. Benfotiamine can be used for the research of various secondary diabetic complications. Benfotiamine also can be used in infectious diseases such as HIV and COVID-19. | ||||||||||||||||||||
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Thiamine disulfide dinitrate | Thiamine Disulfide Nitrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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Dibenzoyl Thiamine | 99.83% | Dibenzoyl Thiamine (Bentiamine), a derivative of thiamine, is rapidly absorbed into the body and converted to thiamine. | ||||||||||||||||||||
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Thiamine disulfide (Standard) | 99.22% | Thiamine disulfide (Standard) is the analytical standard of Thiamine disulfide. This product is intended for research and analytical applications. Thiamine disulfide, a vitamin B1 derivative, is an oxidized dimer of Thiamine. Thiamine disulfide is a potent HIV-1 inhibitor. Thiamine disulfide significantly depresses HIV-1 transactivator (Tat) activity. | ||||||||||||||||||||
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Sulbutiamine | 98.0% | Sulbutiamine is a synthetic analogue of vitamin B1 used for the treatment of asthenia. | ||||||||||||||||||||
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Cycotiamine | Cycotiamine is an S-acylated thiamine derivative with antiplasmodial activity. Cycotiamine inhibits the proliferation of Plasmodium falciparum and Plasmodium knowlesi. Cycotiamine can be used in malaria-related research. | |||||||||||||||||||||
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Allithiamine | 96.78% | Allithiamine is a thiamin derivative with absorption characteristics similar to fat-soluble vitamins. Allithiamine acts as a cofactor precursor for thiamin pyrophosphate (TPP), which participates in carbohydrate metabolism by supporting the pyruvate dehydrogenase (PDH) complex to facilitate pyruvate entry into the tricarboxylic acid (TCA) cycle as acetyl CoA. Allithiamine can be used for researching thiamin metabolism. | ||||||||||||||||||||
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References
- [1]. Fursultiamine alleviates choroidal neovascularization by suppressing inflammation and metabolic reprogramming
- [2]. Kobayashi T, et al. Fursultiamine, a vitamin B1 derivative, enhances chondroprotective effects of glucosamine hydrochloride and chondroitin sulfate in rabbit experimental osteoarthritis. Inflamm Res. 2005 Jun;54(6):249-55. [Content Brief]
