82-76-8
Chemical Structure
ANS
Synonym(s): ANSA; 8-Anilino-1-naphthalenesulfonic acid
- CAS 番号: 82-76-8
- Formula:C16H13NO3S
- Molecular Weight:299.35
IUPAC Name: 8-(phenylamino)naphthalene-1-sulfonic acid
InChIKey: FWEOQOXTVHGIFQ-UHFFFAOYSA-N
SMILES: O=S(O)(C1=CC=CC2=CC=CC(NC3=CC=CC=C3)=C21)=O
Biological Activity: ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (Ki=2.09×106 M-1). ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development[1][2].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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ANS | 98.01% | ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (Ki=2.09×106 M-1). ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development. | ||||||||||||||||||||
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4-Aminodiphenylamine sulfate | 4-Aminodiphenylamine sulfate (Variamine Blue RT sulfate) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. | |||||||||||||||||||||
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ANS ammonium (Standard) | ≥98% | ANS (ammonium) (Standard) is the analytical standard of ANS (ammonium). This product is intended for research and analytical applications. ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine. | ||||||||||||||||||||
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EDANS | 99.90% | EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET). | ||||||||||||||||||||
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N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid | N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid is a fluorescent reagent. | |||||||||||||||||||||
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N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid sodium | N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid sodium (1,8-EDNAS sodium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. | |||||||||||||||||||||
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N-Phenyl-1-naphthylamine | 99.98% | N-Phenyl-1-naphthylamine is a dye that fluoresces strongly when bound to the inner phospholipid bilayer of Gram-negative bacteria. N-Phenyl-1-naphthylamine can be used to measure outer membrane permeability. N-Phenylnaphthalen-1-amine is a fluorescence probe for odorant-binding proteins (OBP) with a dissociation constant of 1.67 μM. N-Phenylnaphthalen-1-amine exhibits an excitation wavelength of 337 nM and an emission wavelength of 407 nM. | ||||||||||||||||||||
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Sodium diphenylamine-4-sulfonate | 99.81% | Sodium diphenylamine-4-sulfonate is an anionic sulfonate aromatic ligand that can serve as an intermediate for research related to organic synthesis. | ||||||||||||||||||||
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N-Phenyl-N'-(2-methylphenyl)-p-phenylenediamine | N-Phenyl-N'-(2-methylphenyl)-p-phenylenediamine is a metal-organic framework (MOF). | |||||||||||||||||||||
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N-(Iodoacetylaminoethyl)-8-naphthylamine-1-sulfonic acid | N-(Iodoacetylaminoethyl)-8-naphthylamine-1-sulfonic acid is a biochemical reagent. | |||||||||||||||||||||
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References
- [1]. Polak J, et al. Bioactive Properties of a Novel Antibacterial Dye Obtained from Laccase-Mediated Oxidation of 8-Anilino-1-naphthalenesulfonic Acid. Molecules. 2022 Jan 13;27(2):487. [Content Brief]
- [2]. Brown ML, et al. Use of 8-anilino-1-naphthalenesulfonic acid in radioimmunoassay of triiodothyronine. J Pharm Sci. 1974 Aug;63(8):1214-7. [Content Brief]