827-61-2
Chemical Structure
Aceclidine
Synonym(s): Quinuclidin-3-yl acetate
- CAS No.: 827-61-2
- Formula:C9H15NO2
- Molecular Weight:169.22
IUPAC Name: (1s,4s)-quinuclidin-3-yl acetate
InChIKey: WRJPSSPFHGNBMG-UHFFFAOYSA-N
SMILES: CC(OC1C[N@@]2CC[C@H]1CC2)=O
Biological Activity: Aceclidine (Quinuclidin-3-yl acetate) is a modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC50: 40 μM). Aceclidine is a cycloplegic agent, a surfactant, a tonicity adjustor and optionally a viscosity enhancer and an antioxidant. Aceclidine has the potential for the research of disorders such as refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Aceclidine | 98.0% | Aceclidine (Quinuclidin-3-yl acetate) is a modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC50: 40 μM). Aceclidine is a cycloplegic agent, a surfactant, a tonicity adjustor and optionally a viscosity enhancer and an antioxidant. Aceclidine has the potential for the research of disorders such as refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia. | ||||||||||||||||||||
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Similarity Score 0.97
HY-32067AAceclidine hydrochloride -
Similarity Score 0.76
HY-128855Talsaclidine -
Similarity Score 0.63
HY-125700Baogongteng A -
Similarity Score 0.61
HY-N7132R(-)-Menthyl acetate (Standard) -
Similarity Score 0.61
HY-W317408(+)-Menthyl acetate -
Similarity Score 0.61
HY-W541015(±)-Menthyl acetate -
Similarity Score 0.61
HY-W004415Umeclidinium bromide impurity 8 -
Similarity Score 0.60
HY-N4001Isoboonein acetate -
Similarity Score 0.59
HY-B1918(+)-Bornyl acetate -
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References
- [1]. Gerald Horn, et al. Storage Stable Compositions and Methods for the Treatment of Refractive Errors of the Eye. Patent US20150290125A1.
- [2]. Thomas G. Gant, et al. Imidazole modulators of muscarinic acetylcholine receptor m3. Patent US20110091459A1.
- [3]. Cui Y, et al. Enhancement of memory function in aged mice by a novel derivative of xanomeline. Cell Res. 2008 Nov;18(11):1151-3. [Content Brief]
