839712-12-8
839712-12-8
Chemical Structure
Cariprazine
Synonym(s): RGH-188
- CAS No.: 839712-12-8
- Formula:C21H32Cl2N4O
- Molecular Weight:427.41
IUPAC Name: 3-((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)-1,1-dimethylurea
InChIKey: KPWSJANDNDDRMB-QAQDUYKDSA-N
SMILES: O=C(N[C@H]1CC[C@H](CCN2CCN(C3=CC=CC(Cl)=C3Cl)CC2)CC1)N(C)C
Biological Activity: Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cariprazine | 99.67% | Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). | ||||||||||||||||||||
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Cariprazine (Standard) | ≥98% | Cariprazine (Standard) is the analytical standard of Cariprazine. This product is intended for research and analytical applications. Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). | ||||||||||||||||||||
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Cariprazine-d6 | 98.74% | Cariprazine-d6 is a deuterium labeled Cariprazine. Cariprazine Cariprazine is an antipsychotic agent that exhibits high affinity for the D3 (Ki of 0.085 nM) and D2 (Ki of 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki of 2.6 nM). | ||||||||||||||||||||
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Cariprazine-d8 | Cariprazine-d8-1 (RGH-188-d8-1) is the deuterium labeled Cariprazine (HY-14763). Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). | |||||||||||||||||||||
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Cariprazine-d8 | 98.77% | Cariprazine-d8 is a deuterium labeled Cariprazine. Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-14763ACariprazine hydrochloride -
Similarity Score 0.91
HY-100656ASDesmethyl cariprazine-d8 -
Similarity Score 0.91
HY-100658SDidesmethyl cariprazine-d8 -
Similarity Score 0.89
HY-100656Desmethyl cariprazine -
Similarity Score 0.89
HY-100658Didesmethyl cariprazine -
Similarity Score 0.86
HY-177122Raxlaprazine etomoxil -
Similarity Score 0.84
HY-183776Dopamine D3 receptor agonist-2 -
Similarity Score 0.83
HY-156239Dopamine D3 receptor ligand-5 -
Similarity Score 0.81
HY-W724128Cariprazine N-oxide -
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