Cariprazine-d8
Based on 1 Customer Validation
Cariprazine-d8-1 (RGH-188-d8-1) is the deuterium labeled Cariprazine (HY-14763). Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
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- CAS No.: 1308278-69-4
- Formule: C21H24D8Cl2N4O
- Masse moléculaire:435.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1308278-69-4
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Unlabeled CAS 839712-12-8
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Masse moléculaire 435.46
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Formule C21H24D8Cl2N4O
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SMILES
ClC1=C(C=CC=C1Cl)N2CCN(CC2)C([2H])(C[C@H]3CC[C@@H](CC3)NC(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)[2H]
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Synonyms
RGH-188-d8
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)