84807-90-9

12(S)-HETE-d<sub>8</sub> Chemical Structure
84807-90-9

Chemical Structure

12(S)-HETE-d8

  • CAS No.: 84807-90-9
  • Formula:C20H24D8O3
  • Molecular Weight:328.52

IUPAC Name: (S,5Z,8Z,10E,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoic-5,6,8,9,11,12,14,15-d8 acid

InChIKey: ZNHVWPKMFKADKW-OPXGWVKSSA-N

SMILES: CCCCC/C([2H])=C([2H])\C[C@]([2H])(O)/C([2H])=C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCC(O)=O

Biological Activity: 12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. 12(S)-HETE-d8 is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE-d8 is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.

Cat. No. Product Name Purity Description Pricing
HY-123023 		12(S)-HETE-d8 12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. 12(S)-HETE-d8 is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE-d8 is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.
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HY-124404A 		12(S)-HETE 99.10% 12(S)-HETE is a metabolite of Arachidonic acid, AA (HY-109590). 12(S)-HETE promotes ERK and P38 MAPK phosphorylation, stimulates DNA synthesis and cell proliferation in cancer cells. 12(S)-HETE facilitates wound healing of injured murine-lung-derived microvascular endothelial cell monolayers. 12(S)-HETE can be used for the research of pancreatic cancer.
The product specifications provided below refer solely to the active content of 12(S)-HETE.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

Keywords