853299-07-7
853299-07-7
Chemical Structure
AUZ 454
Synonym(s): K03861
- CAS No.: 853299-07-7
- Formula:C24H26F3N7O2
- Molecular Weight:501.50
IUPAC Name: 1-(4-((2-aminopyrimidin-4-yl)oxy)phenyl)-3-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)urea
InChIKey: PWDLXPJQFNVTNL-UHFFFAOYSA-N
SMILES: NC1=NC(OC2=CC=C(NC(NC3=CC(C(F)(F)F)=C(CN4CCN(C)CC4)C=C3)=O)C=C2)=CC=N1
Biological Activity: AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 8.2 nM. AUZ 454 (K03861) inhibits CDK2 activity by competing with binding of activating cyclins.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AUZ 454 | 99.15% | AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 8.2 nM. AUZ 454 (K03861) inhibits CDK2 activity by competing with binding of activating cyclins. | ||||||||||||||||||||
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