853299-07-7

AUZ 454 Chemical Structure
853299-07-7

Chemical Structure

AUZ 454

Synonym(s): K03861

  • CAS No.: 853299-07-7
  • Formula:C24H26F3N7O2
  • Molecular Weight:501.50

IUPAC Name: 1-(4-((2-aminopyrimidin-4-yl)oxy)phenyl)-3-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)urea

InChIKey: PWDLXPJQFNVTNL-UHFFFAOYSA-N

SMILES: NC1=NC(OC2=CC=C(NC(NC3=CC(C(F)(F)F)=C(CN4CCN(C)CC4)C=C3)=O)C=C2)=CC=N1

Biological Activity: AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 8.2 nM. AUZ 454 (K03861) inhibits CDK2 activity by competing with binding of activating cyclins.

Cat. No. Product Name Purity Description Pricing
HY-15004 		AUZ 454 99.15% AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 8.2 nM. AUZ 454 (K03861) inhibits CDK2 activity by competing with binding of activating cyclins.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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