861875-60-7
861875-60-7
Chemical Structure
NVP-BAW2881
Synonym(s): BAW2881
- CAS No.: 861875-60-7
- Formula:C22H15F3N4O2
- Molecular Weight:424.38
IUPAC Name: 6-((2-aminopyrimidin-4-yl)oxy)-N-(3-(trifluoromethyl)phenyl)-1-naphthamide
InChIKey: MLLQJNIKDWEEFT-UHFFFAOYSA-N
SMILES: O=C(C1=C2C=CC(OC3=NC(N)=NC=C3)=CC2=CC=C1)NC4=CC=CC(C(F)(F)F)=C4
Biological Activity: NVP-BAW2881 (BAW2881) is a potent and selective VEGFR2 inhibitor with an IC50 of 9 nM[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NVP-BAW2881 | 98.54% | NVP-BAW2881 (BAW2881) is a potent and selective VEGFR2 inhibitor with an IC50 of 9 nM. | ||||||||||||||||||||
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References
- [1]. Bold G, et al. A Novel Potent Oral Series of VEGFR2 Inhibitors Abrogate Tumor Growth by Inhibiting Angiogenesis. J Med Chem. 2016 Jan 14;59(1):132-46. [Content Brief]
- [2]. Halin C, et al. Inhibition of chronic and acute skin inflammation by treatment with a vascular endothelial growth factor receptor tyrosine kinase inhibitor. Am J Pathol. 2008 Jul;173(1):265-77. [Content Brief]
Keywords
