90-29-9
90-29-9
Chemical Structure
Pseudobaptigenin
- CAS No.: 90-29-9
- Formula:C16H10O5
- Molecular Weight:282.25
InChIKey: KNJNBKINYHZUGC-UHFFFAOYSA-N
SMILES: O=C1C2=CC=C(C=C2OC=C1C3=CC4=C(OCO4)C=C3)O
Biological Activity: Pseudobaptigenin is a natural isoflavone polyphenolic compound. Pseudobaptigenin is generated through the CYP76F319-catalyzed conversion of Calycosin (HY-N0519) and can serve as a precursor for phytoalexin synthesis. Pseudobaptigenin is predicted to have potential as an inhibitor of ER, PR, and HER2. Pseudobaptigenin can be used in research on breast cancer and metabolism-related diseases[1][2].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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Pseudobaptigenin | 98.41% | Pseudobaptigenin is a natural isoflavone polyphenolic compound. Pseudobaptigenin is generated through the CYP76F319-catalyzed conversion of Calycosin (HY-N0519) and can serve as a precursor for phytoalexin synthesis. Pseudobaptigenin is predicted to have potential as an inhibitor of ER, PR, and HER2. Pseudobaptigenin can be used in research on breast cancer and metabolism-related diseases. | ||||||||||||||||||||
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7,3',4'-Trihydroxyisoflavone | 99.83% | 7,3',4'-Trihydroxyisoflavone, a major metabolite of Daidzein, is an ATP-competitive inhibitor of Cot (Tpl2/MAP3K8) and MKK4. 7,3',4'-Trihydroxyisoflavone has anticancer, anti-angiogenic, chemoprotective, and free radical scavenging activities. | ||||||||||||||||||||
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Daidzein | 99.81% | Daidzein is a soy isoflavone, which acts as a PPAR activator. | ||||||||||||||||||||
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Formononetin (Standard) | 98.79% | Formononetin (Standard) is the analytical standard of Formononetin. This product is intended for research and analytical applications. Formononetin is a potent FGFR2 inhibitor with an IC50 of ~4.31 μM. Formononetin potently inhibits angiogenesis and tumor growth. | ||||||||||||||||||||
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Calycosin | 99.96% | Calycosin is a compound that can be isolated from Radix Astragali. Calycosin has strong antioxidant, anti-inflammatory and apoptosis-modulating effects. Calycosin can be used for the research of ovarian cancer and breast cancer. | ||||||||||||||||||||
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2′-Hydroxydaidzein | 96.04% | 2′-Hydroxydaidzein is a metabolite. 2′-Hydroxydaidzein inhibits the release of chemical mediator from inflammatory cells. 2′-Hydroxydaidzein significantly inhibits lysozyme and β-glucuronidase release from rat neutrophils, which is stimulated with fMLP/CB, respectively. | ||||||||||||||||||||
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3'-Methoxydaidzein | 99.67% | 3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels. | ||||||||||||||||||||
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7,3'-Dihydroxy-5'-methoxyisoflavone | 7,3'-Dihydroxy-5'-methoxyisoflavone (Pterosonin E) is an arylcoumarin. 7,3'-Dihydroxy-5'-methoxyisoflavone can be used for various biochemical studies. | |||||||||||||||||||||
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7-Hydroxyisoflavone | 99.75% | 7-Hydroxyisoflavone is an enterovirus replication inhibitor. 7-Hydroxyisoflavone inhibits enterovirus 71 viral RNA synthesis, viral protein synthesis, and early replication steps. 7-Hydroxyisoflavone also inhibits coxsackievirus replication. 7-Hydroxyisoflavone enhances AMPK activity and prevents serum-induced reduction of AMPK phosphorylation. 7-Hydroxyisoflavone can be used in research related to enterovirus infection. | ||||||||||||||||||||
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7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one | 7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one is a dual agonist of PPARα and PPARγ, with an EC50 of 23.10 μM for human PPARα and an EC50 of 22.29 μM for human PPARγ. 7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one regulates the expression of lipid metabolism-related genes via PPARα, and modulates the expression of genes associated with glucose homeostasis and adipogenesis via PPARγ. 7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one can be used in the research of type 2 diabetes and metabolic syndrome. | |||||||||||||||||||||
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2′-Hydroxyformononetin | 2 '-Hydroxyformononetin is an isoflavone compound. 2 '-Hydroxyformononetin may have anti-inflammatory and antioxidant activities. | |||||||||||||||||||||
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References
- [1]. Raytek LM, et al. Discovery of pseudobaptigenin synthase in fungal-infected Trifolium pratense roots. The Plant journal : for cell and molecular biology. 2026 Jul;127(1):e71018.
- [2]. Ray S, et al. Identification of pseudobaptigenin as a novel polyphenol-based multi-target antagonist of different hormone receptors for breast cancer therapeutics. Journal of biomolecular structure & dynamics. 2024 Jul;42(11):5502-5514.
