92-35-3
92-35-3
Chemical Structure
Thiochrome
- CAS No.: 92-35-3
- Formula:C12H14N4OS
- Molecular Weight:262.33
IUPAC Name: 2-(2,7-dimethyl-5H-pyrimido[4,5-d]thiazolo[3,2-a]pyrimidin-8-yl)ethan-1-ol
InChIKey: GTQXMAIXVFLYKF-UHFFFAOYSA-N
SMILES: OCCC1=C(C)N2CC3=CN=C(C)N=C3N=C2S1
Biological Activity: Thiochrome, a natural oxidation product and metabolite of thiamine, is a selective M4 muscarinic receptor of acetylcholine (ACh) affinity enhancer. Thiochrome has neutral cooperativity with ACh at M1 to M3 receptors[1][2].
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Thiochrome | 99.89% | Thiochrome, a natural oxidation product and metabolite of thiamine, is a selective M4 muscarinic receptor of acetylcholine (ACh) affinity enhancer. Thiochrome has neutral cooperativity with ACh at M1 to M3 receptors. | ||||||||||||||||||||
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Thiochrome (Standard) | ≥98% | Thiochrome (Standard) is the analytical standard of Thiochrome. This product is intended for research and analytical applications. Thiochrome, a natural oxidation product and metabolite of thiamine, is a selective M4 muscarinic receptor of acetylcholine (ACh) affinity enhancer. Thiochrome has neutral cooperativity with ACh at M1 to M3 receptors. | ||||||||||||||||||||
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References
- [1]. Petrov SA, et al. Administration of Thiamine and Thiochrome Enhanced Reproduction of Chlorella, Drosophila melanogaster, and Danio. J Nutr Sci Vitaminol (Tokyo). 2016;62(1):6-11. [Content Brief]
- [2]. Lazareno S, et al. Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity. Mol Pharmacol. 2004 Jan;65(1):257-66. [Content Brief]
