929634-33-3

ADAMTS-5 Inhibitor Chemical Structure
929634-33-3

Chemical Structure

ADAMTS-5 Inhibitor

  • CAS No.: 929634-33-3
  • Formula:C16H11ClF3N3OS3
  • Molecular Weight:449.92

IUPAC Name: (Z)-5-((5-((4-chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one

InChIKey: CVYPRDPBCXSVBN-WDZFZDKYSA-N

SMILES: O=C1NC(S/C1=C\C2=C(SCC3=CC=C(Cl)C=C3)N(C)N=C2C(F)(F)F)=S

Biological Activity: ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 µM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1)[1].

Cat. No. Product Name Purity Description Pricing
HY-114996 		ADAMTS-5 Inhibitor 99.59% ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 µM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1).
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