930455-91-7
930455-91-7
Chemical Structure
RGB-1
- CAS No.: 930455-91-7
- Formula:C22H12N4O4S2
- Molecular Weight:460.49
InChIKey: QNXKYGQXHUFVRZ-UHFFFAOYSA-N
SMILES: O=C1C2=C(SC=C2C3=CC=CO3)N=C4N1CC5=NC6=C(C(N5C4)=O)C(C7=CC=CO7)=CS6
Biological Activity: RGB-1 selectively binds to and stabilizes RNA G-quadruplex structures, and reduces the expression of the NRAS proto-oncogene in breast cancer cells. RGB-1 can serve as a tool for investigating the cellular functions of RNA G-quadruplex structures and identifying novel mRNA G-quadruplex-forming sequences. RGB-1 is applicable for breast cancer research[1].
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RGB-1 | RGB-1 selectively binds to and stabilizes RNA G-quadruplex structures, and reduces the expression of the NRAS proto-oncogene in breast cancer cells. RGB-1 can serve as a tool for investigating the cellular functions of RNA G-quadruplex structures and identifying novel mRNA G-quadruplex-forming sequences. RGB-1 is applicable for breast cancer research. | |||||||||||||||||||||
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References
Keywords
