935666-88-9
935666-88-9
Chemical Structure
AZD-1480
- CAS No.: 935666-88-9
- Formula:C14H14ClFN8
- Molecular Weight:348.77
IUPAC Name: (S)-5-chloro-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
InChIKey: PDOQBOJDRPLBQU-QMMMGPOBSA-N
SMILES: ClC1=C(N=C(N=C1)N[C@@H](C)C2=NC=C(C=N2)F)NC3=NNC(C)=C3
Biological Activity: AZD-1480 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50s of 1.3 nM and <0.4 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZD-1480 | 99.74% | AZD-1480 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50s of 1.3 nM and <0.4 nM, respectively. | ||||||||||||||||||||
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AZD-1480 (Standard) | ≥98% | AZD-1480 (Standard) is the analytical standard of AZD-1480 (HY-10193). This product is intended for research and analytical applications. AZD-1480 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50s of 1.3 nM and <0.4 nM, respectively. | ||||||||||||||||||||
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References
Keywords
