96-17-3
96-17-3
Chemical Structure
2-Methylbutanal
Synonym(s): 2-Methylbutyraldehyde
- No. CAS: 96-17-3
- Formula:C5H10O
- Molecular Weight:86.13
IUPAC Name: 2-methylbutanal
InChIKey: BYGQBDHUGHBGMD-UHFFFAOYSA-N
SMILES: CCC(C)C=O
Biological Activity: 2-Methylbutanal (2-Methylbutyraldehyde) is a short-chain aliphatic aldehyde and a characteristic volatile biomarker that can be used to detect the urinary tract pathogen Proteus. 2-Methylbutanal is an orally active CaSR activator and ENO1 inhibitor (Kd = 4.92 μM). 2-Methylbutanal activates oral CaSR to enhance the umami and salty taste of food. 2-Methylbutanal downregulates YAP1 by inhibiting the RNA-binding function of ENO1, thereby upregulating HPGD and reducing PGE2 production, ultimately relieving immunosuppression to promote the infiltration and activation of intratumoral CD8+ T cells. 2-Methylbutanal can be used in research on bacterial infections, colorectal cancer, and food flavor modulation[1][2][3][4][5].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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2-Methylbutanal | 98.43% | 2-Methylbutanal (2-Methylbutyraldehyde) is a short-chain aliphatic aldehyde and a characteristic volatile biomarker that can be used to detect the urinary tract pathogen Proteus. 2-Methylbutanal is an orally active CaSR activator and ENO1 inhibitor (Kd = 4.92 μM). 2-Methylbutanal activates oral CaSR to enhance the umami and salty taste of food. 2-Methylbutanal downregulates YAP1 by inhibiting the RNA-binding function of ENO1, thereby upregulating HPGD and reducing PGE2 production, ultimately relieving immunosuppression to promote the infiltration and activation of intratumoral CD8+ T cells. 2-Methylbutanal can be used in research on bacterial infections, colorectal cancer, and food flavor modulation. | ||||||||||||||||||||
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2-Methylbutanal-d9 | ||||||||||||||||||||||
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Isocaproaldehyde | 97.0% | Isocaproaldehyde is a product of side-chain cleavage of cholesterol. Isocaproaldehyde is an endogenous specific substrate of mouse vas deferens protein (MVDP). | ||||||||||||||||||||
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L-Lactaldehyde | L-Lactaldehyde ((2S)-Hydroxypropanal) is a chiral aldehyde, metabolic intermediate, and enzyme substrate. L-Lactaldehyde is oxidized to L-lactate by NAD-dependent lactaldehyde dehydrogenase. L-Lactaldehyde is reduced to L-1,2-propanediol by NADH/NADPH-dependent oxidoreductases. L-Lactaldehyde is used in studies of microbial sugar metabolism and carbonyl metabolism. | |||||||||||||||||||||
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5-Methyl-3-heptanone | 5-Methyl-3-heptanone is an intermediate for drug synthesis. | |||||||||||||||||||||
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2-Methylbutanoic acid | 99.98% | 2-Methylbutanoic acid is a chemical intermediate for a variety of applications such as plasticizers, lubricants and pharmaceuticals. | ||||||||||||||||||||
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3-Methylvaleric acid (Standard) | 99.54% | 3-Methylvaleric acid (Standard) is an analytical standard form of 3-Methylvaleric acid (HY-W010513). This product is intended for research and analytical applications. 3-Methylvaleric Acid is a branched alkanoic acid. 3-Methylvaleric Acid can be utilized by Pseudomonas citronettotis as a sole carbon source for its growth. 3-Methylvaleric Acid derivatives exhibit anti-hyperalgesic and anticonvulsant activities. | ||||||||||||||||||||
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5-Methylhept-2-en-4-one | 5-Methylhept-2-en-4-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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(R)-(-)-2-Butanol | 99.98% | (R)-(-)-2-Butanol is the isomer of 2-Butanol, which is found in the females of the white grub beetle, Dasylepida ishigakiensis, to attract males. (R)-(-)-2-Butanol is an intermediate of pharmaceutical synthesis by coupling. | ||||||||||||||||||||
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(S)-(-)-2-Methylbutanol | 99.91% | (S)-(-)-2-Methylbutanol is a S-isomer of 2-Methylbutanol. | ||||||||||||||||||||
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3-Methylpentan-1-ol | 98.57% | 3-Methylpentan-1-ol is a Hexanol isomer. | ||||||||||||||||||||
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References
- [1]. Kitajima S, et al. Volatile Short-Chain Aliphatic Aldehydes Act as Taste Modulators through the Orally Expressed Calcium-Sensing Receptor CaSR. Molecules (Basel, Switzerland). 2023 Jun 06;28(12):4585.
- [2]. Moreira MTG, et al. Aldehyde Accumulation in Aged Alcoholic Beer: Addressing Acetaldehyde Impacts on Upper Aerodigestive Tract Cancer Risks. International journal of molecular sciences. 2022 Nov 16;23(22):14147.
- [3]. Aro R, et al. Endogenous Synthesis of Tetrahydroisoquinoline Derivatives from Dietary Factors: Neurotoxicity Assessment on a 3D Neurosphere Culture. Molecules (Basel, Switzerland). 2022 Nov 02;27(21):7443.
- [4]. Al-Fatimi M. Volatile constituents, et al. from Yemen. J. Pharm. Res. Int. 2018 Jan 1;23(10).
- [5]. Kam S, et al. 2-methylbutanal remodels arachidonic acid metabolism and antitumor immunity through ENO1 in colorectal cancer. Journal of Translational Medicine. 2026 Aug 11.
