98-96-4
98-96-4
Chemical Structure
Pyrazinamide
Synonym(s): Pyrazinecarboxamide; Pyrazinoic acid amide
- CAS No.: 98-96-4
- Formula:C5H5N3O
- Molecular Weight:123.11
IUPAC Name: pyrazine-2-carboxamide
InChIKey: IPEHBUMCGVEMRF-UHFFFAOYSA-N
SMILES: O=C(C1=NC=CN=C1)N
Biological Activity: Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Pyrazinamide | 99.93% | Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Pyrazinamide (Standard) | 99.99% | Pyrazinamide (Standard) is the analytical standard of Pyrazinamide. This product is intended for research and analytical applications. Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Pyrazinamide-d3 | 99.23% | Pyrazinamide-d3 is deuterium labeled Pyrazinamide. Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Pyrazinamide-15N,d3 | Pyrazinamide-15N,d3 (Pyrazinecarboxamide-15N,d3) is the deuterated, 15N-labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Pyrazinamide-13C,15N | Pyrazinamide-13C,15N is 15N and 13C labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Picolinamide (Standard) | ≥98% | Picolinamide (Standard) is the analytical standard of Picolinamide. This product is intended for research and analytical applications. Picolinamide (2-Picolinamide) is an inhibitor of Poly(ADP-ribose) synthetase of nuclei from rat pancreatic islet cells. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
5-Aminopyrimidine-d3 | 5-Aminopyrimidine-d3 is the deuterated form of 5-Aminopyrimidine. 5-Aminopyrimidine is a biochemical reagent that can serve as a biomaterial or an organic compound for research related to life sciences. Its derivatives exhibit antioxidant activity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
2-Pyrazinecarboxylic acid | 99.89% | 2-Pyrazinecarboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Pyrazinecarboxylic acid-d3 | Pyrazinecarboxylic acid-d3 is the deuterium labeled Pyrazinecarboxylic acid. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Nicotinamide | 99.98% | Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Nicotinamide-d4 | 99.94% | Nicotinamide-d4 is the deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Nicotinamide-15N,13C3 | Nicotinamide-15N,13C3 is the 13C-labeled and 15N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Nicotinamide-13C6 | 99.90% | Nicotinamide-13C6 is the 13C-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Nicotinamide-d3 | Nicotinamide-d3 (Niacinamide-d3) is deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Isoniazid-d4 | 99.86% | Isoniazid-d4 is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Isonicotinic acid-d4 | 98.12% | Isonicotinic acid-d4 is the deuterium labeled Isonicotinic acid (HY-I0736). Isonicotinic acid is a pyridine carboxylic acid compound and also a metabolite of Isoniazid (HY-B0329). Derivatives of Isonicotinic acid exhibit antiviral activity against influenza viruses. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Acetylpyrazine | 98.45% | Acetylpyrazine (2-Acetylpyrazine) is used to form many polycyclic compounds, as useful structures in pharmaceuticals and perfumes. Acetylpyrazine is a component of the folates (vitamin B compounds). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Isonicotinamide (Standard) | 99.75% | Isonicotinamide (Standard) is the analytical standard of Isonicotinamide. This product is intended for research and analytical applications. Isonicotinamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Isonicotinamide-d4 | 99.91% | Isonicotinamide-d4 is the deuterium labeled Isonicotinamide. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Pyrazine-d4 | Pyrazine-d4 is the deuterium labeled Pyrazine. Pyrazine is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
2-Methylpyrazine-d6 | 98.81% | 2-Methylpyrazine-d6 is the deuterium labeled 2-Methylpyrazine. 2-Methylpyrazine is a kind of alkylpyrazine that can be identified in roasted red pepper seed oils. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Pyrazine-2-carbothioamide | 99.63% | Pyrazine-2-carbothioamide is an effective antituberculosis agent with inhibitory activity against mycobacterium in vitro. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Picolinic acid-d4 | 99.99% | Ppicolinic-3,4,5,6-d4 acid is the deuterium labeled Ppicolinic acid. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Pyrazinoylguanidine | Pyrazinoylguanidine (PZG) is an analogue of the potassium sparing diuretic, Amiloride (HY-B0285). Pyrazinoylguanidine can lower the systolic and diastolic blood pressure of patients with primary hypertension, has a certain effect on reducing heart rate, and does not affect the concentrations of electrolytes such as sodium, potassium, and chloride in the blood serum. Pyrazinoylguanidine can reduce the hyperglycemia and hyperinsulinemia in type 2 diabetes, reduce the levels of triglycerides, cholesterol, and free fatty acids, and reverse the hyperglycemia and hyperlipidemia induced by thiazide diuretics, such as Hydrochlorothiazide (HY-B0252). Pyrazinoylguanidine ican nhibit the reabsorption of urea by the renal tubules, thereby increasing the clearance rate and excretion volume of urea, reducing the serum urea concentration, and minimizing its toxic accumulation. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Nicotinamide-15N | 99.65% | Nicotinamide-15N (Niacinamide-15N) is the deuterium labeled Nicotinamide (HY-B0150). Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
