1. Anti-infection
  2. Bacterial
  3. Pyrazine-2-carbothioamide

Pyrazine-2-carbothioamide is an effective antituberculosis agent with inhibitory activity against mycobacterium in vitro.

For research use only. We do not sell to patients.

Pyrazine-2-carbothioamide

Pyrazine-2-carbothioamide Chemical Structure

CAS No. : 4604-72-2

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Description

Pyrazine-2-carbothioamide is an effective antituberculosis agent with inhibitory activity against mycobacterium in vitro[1].

Molecular Weight

139.18

Formula

C5H5N3S

CAS No.
Appearance

Solid

SMILES

S=C(C1=NC=CN=C1)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (718.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.1849 mL 35.9247 mL 71.8494 mL
5 mM 1.4370 mL 7.1849 mL 14.3699 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.63%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.1849 mL 35.9247 mL 71.8494 mL 179.6235 mL
5 mM 1.4370 mL 7.1849 mL 14.3699 mL 35.9247 mL
10 mM 0.7185 mL 3.5925 mL 7.1849 mL 17.9624 mL
15 mM 0.4790 mL 2.3950 mL 4.7900 mL 11.9749 mL
20 mM 0.3592 mL 1.7962 mL 3.5925 mL 8.9812 mL
25 mM 0.2874 mL 1.4370 mL 2.8740 mL 7.1849 mL
30 mM 0.2395 mL 1.1975 mL 2.3950 mL 5.9875 mL
40 mM 0.1796 mL 0.8981 mL 1.7962 mL 4.4906 mL
50 mM 0.1437 mL 0.7185 mL 1.4370 mL 3.5925 mL
60 mM 0.1197 mL 0.5987 mL 1.1975 mL 2.9937 mL
80 mM 0.0898 mL 0.4491 mL 0.8981 mL 2.2453 mL
100 mM 0.0718 mL 0.3592 mL 0.7185 mL 1.7962 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Pyrazine-2-carbothioamide
Cat. No.:
HY-W129661
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