Catalpalactone
Based on 1 publication(s) in Google Scholar
Catalpalactone has anti-inflammatory effect. Catalpalactone inhibits LPS-induced NO production and iNOS expression in RAW264.7 cells, and also inhibits IRF3, NF-κB, and IFN-β/STAT-1 activation. Catalpalactone also inhibits dopamine biosynthesis by reducing tyrosine hydroxylase (TH) and aromatic-l-amino acid decarboxylase (AADC) activities.
For research use only. We do not sell to patients.
- CAS No.: 1585-68-8
- Formula: C15H14O4
- Molecular Weight:258.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Catalpalactone
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Biological Activity
Chemical Information
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CAS No. 1585-68-8
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Molecular Weight 258.27
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Formula C15H14O4
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SMILES
O=C1OC(C2=CCC(C)(C)OC2=O)C3=C1C=CC=C3
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Eur J Med Res
Catalpalactone protects rats nerve function from hypoxic lesion by polarizing microglial cells toward M2 phenotype. [Abstract]2025 Feb 12;30(1):96. PMID: 39940010
Purity & Documentation
References
[1]. Kim HY, et al. Anti-Inflammatory Effects of Catalpalactone Isolated from Catalpa ovata in LPS-Induced RAW264.7 Cells. Molecules. 2019 Mar 29;24(7):1236. [Content Brief]
[2]. Huang HS, et al. Effects of catalpalactone on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells. Environ Toxicol Pharmacol. 2008 Jul;26(1):86-91. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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