Cathepsin L-IN-4
Cathepsin L-IN-4 is an inhibitor of cathepsin L with IC50 at nanomolar concentrations.
For research use only. We do not sell to patients.
- CAS No.: 161709-56-4
- Formula: C27H29N3O4S
- Molecular Weight:491.60
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Cathepsin Isoforms
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Biological Activity
Description
IC50 & Target
|
cathepsin L |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | ED50 |
21 μM
Compound: 10b
|
Cytotoxicity against human HL60 cells
Cytotoxicity against human HL60 cells
|
[PMID: 23611656] |
Chemical Information
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CAS No. 161709-56-4
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Appearance Solid
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Molecular Weight 491.60
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Formula C27H29N3O4S
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Color White to off-white
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Synonyms
1-Naphthalenesulfonyl-Ile-Trp-CHO
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Sequence
{1-Naphthalenesulfonyl}-Ile-Trp-CHO
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Sequence Shortening
{1-Naphthalenesulfonyl}-IW-CHO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)