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Cat. No.: HY-147256

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Cavutilide

(Synonyms: Niferidil free base)

Cavutilide (Niferidil (free base)) is a class III antiarrhythmic agent that inhibits hERG K⁺ channel. Cavutilide has the potential for the study of persistent atrial fibrillation.

For research use only. We do not sell to patients.

CAS No.: 1276186-19-6
Formula: C₂₂H₂₆FN₃O₃
Molecular Weight:399.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Cavutilide Chemical Structure

CAS No.: 1276186-19-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Cavutilide (Niferidil (free base)) is a class III antiarrhythmic agent that inhibits hERG K⁺ channel. Cavutilide has the potential for the study of persistent atrial fibrillation^[1]^[2].

Chemical Information

CAS No. 1276186-19-6
Molecular Weight 399.46
Formula C₂₂H₂₆FN₃O₃
SMILES

O=C(NC(C1=CC=C(F)C=C1)CC2CCN(CC)CC2)C3=CC=C([N+]([O-])=O)C=C3
Synonyms

Niferidil free base
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. WHO Drug Information, Vol. 36, No. 2, 2022.

[2]. Abramochkin DV, et al. Characterization of hERG K+ channel inhibition by the new class III antiarrhythmic drug cavutilide. Naunyn Schmiedebergs Arch Pharmacol. 2024 Jul;397(7):5093-5104. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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