1. Immunology/Inflammation
  2. NO Synthase
  3. CAY10565

CAY10565 (Compound 3d) is a nitric oxide (NO) donor. CAY10565 releases nitric acid via an acid-catalyzed ring-opening mechanism under acidic conditions. CAY10565 induces vasodilation.

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CAY10565

CAY10565 Chemical Structure

CAS No. : 140379-82-4

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Description

CAY10565 (Compound 3d) is a nitric oxide (NO) donor. CAY10565 releases nitric acid via an acid-catalyzed ring-opening mechanism under acidic conditions. CAY10565 induces vasodilation[1].

In Vitro

CAY10565 (0.8 mM) exhibits a decomposition half-life of 130 min in acidic (pH 5.0) aqueous buffer at 37 °C, making it one of the most stable analogs tested under these conditions[1].
CAY10565 (20 mM) releases nitric oxide under acidic conditions (pH 5.0) with a yield of approximately 9%, a process detectable by the EPR spin-trapping method using [(MGD)2FeII]; it does not release NO under neutral pH conditions[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

209.22

Formula

C9H7NO3S

CAS No.
SMILES

[O-]C1=C([S+]=NO1)C2=CC=C(OC)C=C2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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CAY10565
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HY-181464
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