CEase-IN-1
CEase-IN-1 (Compound A1H3) is a potent and selective cholesterol esterase (CEase) inhibitor with an IC50 of 0.36 μM. CEase-IN-1 can be used for the research of hypercholesterolemia.
For research use only. We do not sell to patients.
- CAS No.: 2985688-68-2
- Formula: C13H15F3N2O2
- Molecular Weight:288.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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CEase 0.36 μM (IC50) |
AChE 45.9 μM (IC50) |
Chemical Information
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CAS No. 2985688-68-2
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Molecular Weight 288.27
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Formula C13H15F3N2O2
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SMILES
O=C(COC1=CC=C(C(F)(F)F)C=C1)N/N=C/CCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)