Ceralasertib (Standard)
Ceralasertib (Standard) is the analytical standard of Ceralasertib (HY-19323). This product is intended for research and analytical applications. Ceralasertib (AZD6738) is an orally active and bioavailable inhibitor of ATR Kinase with an IC50 of 1 nM.
For research use only. We do not sell to patients.
- CAS No.: 1352226-88-0
- Formula: C20H24N6O2S
- Molecular Weight:412.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1352226-88-0
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Molecular Weight 412.51
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Formula C20H24N6O2S
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SMILES
O=[S@@](C1(CC1)C2=NC(C3=C4C(NC=C4)=NC=C3)=NC(N5CCOC[C@H]5C)=C2)(C)=N
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Synonyms
AZD6738 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Vendetti FP, et al. The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of CDDP to resolve ATM-deficient non-small cell lung cancer in vivo. [Content Brief]
[2]. Kim HJ, et al. Anti-tumor activity of the ATR inhibitor AZD6738 in HER2 positive breast cancer cells. Int J Cancer. 2017 Jan 1;140(1):109-119. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)