CFM-4
Based on 1 Customer Validation
CFM-4 is a potent small molecular antagonist of CARP-1/APC-2 binding. CFM-4 prevents CARP-1 binding with APC-2, causes G2M cell cycle arrest, and induces apoptosis with an IC50 range of 10-15 μM. CFM-4 also suppresses growth of drug-resistant human breast cancer cells.
For research use only. We do not sell to patients.
- Purity: 98.85%
- CAS No.: 331458-02-7
- Formula: C22H16ClN3OS
- Molecular Weight:405.90
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Apoptosis Compound Library
HY-L003
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Anti-Cancer Compound Library
HY-L025
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Anti-Breast Cancer Compound Library
HY-L074
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Cell Death Library
HY-L162
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Anti-Drug-Resistant Compound Library
HY-L169
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library
HY-L199
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
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CAS No. 331458-02-7
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Appearance Solid
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Molecular Weight 405.90
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Formula C22H16ClN3OS
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Color Light yellow to yellow
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SMILES
O=C1N(CC2=CC=CC=C2Cl)C3=C(C=CC=C3)C14SC(C5=CC=CC=C5)=NN4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (61.59 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4637 mL | 12.3183 mL | 24.6366 mL | 61.5915 mL |
| 5 mM | 0.4927 mL | 2.4637 mL | 4.9273 mL | 12.3183 mL | |
| 10 mM | 0.2464 mL | 1.2318 mL | 2.4637 mL | 6.1592 mL | |
| 15 mM | 0.1642 mL | 0.8212 mL | 1.6424 mL | 4.1061 mL | |
| 20 mM | 0.1232 mL | 0.6159 mL | 1.2318 mL | 3.0796 mL | |
| 25 mM | 0.0985 mL | 0.4927 mL | 0.9855 mL | 2.4637 mL | |
| 30 mM | 0.0821 mL | 0.4106 mL | 0.8212 mL | 2.0531 mL | |
| 40 mM | 0.0616 mL | 0.3080 mL | 0.6159 mL | 1.5398 mL | |
| 50 mM | 0.0493 mL | 0.2464 mL | 0.4927 mL | 1.2318 mL | |
| 60 mM | 0.0411 mL | 0.2053 mL | 0.4106 mL | 1.0265 mL |
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