6-TRITC
6-TRITC (Tetramethylrhodamine-6-isothiocyanate) is a potent fluorescent tracer. 6-TRITC can be used as an probe for haptenated proteins/peptides for the research of contact allergy. 6-TRITC can be used as a tracer for the confocal imaging in living cells.
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- CAS. Nr.: 80724-20-5
- Formel: C25H21N3O3S
- Molecular Weight:443.52
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Speicherung:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
6-TRITC is relatively photostable and robust toward pH changes[1].
6-TRITC as an extreme sensitizer induces a massive cell proliferation and gave an EC3 value of 0.92 mM (0.040%) in the murine LLNA (local lymph node assay)[1].
6-TRITC (1.0 mg; 2h) can used as fluorescence probe for confocal imaging in Fe3O4@PDA incubated living cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Chemical Information
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CAS. Nr. 80724-20-5
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Appearance Solid
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Molecular Weight 443.52
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Formel C25H21N3O3S
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Color Dark purple to black
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SMILES
CN(C1=CC2=[O+]C3=C(C=CC(N(C)C)=C3)C(C4=CC(N=C=S)=CC=C4C([O-])=O)=C2C=C1)C
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Synonyms
Tetramethylrhodamine-6-isothiocyanate
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (645 KB)
- English - EN (645 KB)
- Français - FR (645 KB)
- Deutsch - DE (645 KB)
- Norwegian - NO (645 KB)
- Español - ES (645 KB)
- Swedish - SV (645 KB)
- Italian - IT (645 KB)
- Korean - KR (645 KB)
- Portuguese - PT (645 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Karlsson I, et al. Peptide Reactivity of Isothiocyanates--Implications for Skin Allergy. Sci Rep. 2016 Feb 17;6:21203. [Content Brief]
[2]. Yue Q ,et al . A versatile ethanol-mediated polymerization of dopamine for efficient surface modification and the construction of functional core-shell nanostructures. J Mater Chem B. 2013 Nov 28;1(44):6085-6093. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
6-TRITC Related Classifications
HY-D0154 Related Classifications
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