Art. -Nr.: HY-122906

JTE-952

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JTE-952 is a potent, oral active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC₅₀ values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis.

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Reinheit: 99.86%
CAS. Nr.: 1255303-54-8
Formel: C₃₀H₃₄N₂O₆
Molecular Weight:518.60

Speicherung:

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

JTE-952 Chemical Structure

CAS. Nr.: 1255303-54-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
- In Vivo
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

IC50: 13 nM (CSF1R), 261 nM (TrkA)^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of full-length human N-terminal His6-tagged IKKbeta expressed in baculovirus infected Sf21 insect cells using IKKtide as substrate Inhibition of full-length human N-terminal His6-tagged IKKbeta expressed in baculovirus infected Sf21 insect cells using IKKtide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of full-length human N-terminal His6-tagged JNK3 expressed in baculovirus infected Sf21 insect cells using ATF2 as substrate Inhibition of full-length human N-terminal His6-tagged JNK3 expressed in baculovirus infected Sf21 insect cells using ATF2 as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of full-length human N-terminal His6-tagged LCK expressed in baculovirus infected Sf21 insect cells using Src peptide as substrate Inhibition of full-length human N-terminal His6-tagged LCK expressed in baculovirus infected Sf21 insect cells using Src peptide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of full-length human N-terminal His6-tagged LYN expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate Inhibition of full-length human N-terminal His6-tagged LYN expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full length C-terminal His6-tagged Cdk2/human full length N-terminal GST-tagged Cyclin A expressed in baculovirus infected Sf21 insect cells using Histone H1 as substrate Inhibition of human full length C-terminal His6-tagged Cdk2/human full length N-terminal GST-tagged Cyclin A expressed in baculovirus infected Sf21 insect cells using Histone H1 as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full length His6-tagged CK2alpha expressed in baculovirus infected Sf21 insect cells using Casein Kinase 2 substrate peptide Inhibition of human full length His6-tagged CK2alpha expressed in baculovirus infected Sf21 insect cells using Casein Kinase 2 substrate peptide	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full length N-terminal GST-tagged CHK1 expressed in baculovirus infected Sf21 insect cells using CHKtide as substrate Inhibition of human full length N-terminal GST-tagged CHK1 expressed in baculovirus infected Sf21 insect cells using CHKtide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full-length C-terminal His6-tagged ZAP70 expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate Inhibition of human full-length C-terminal His6-tagged ZAP70 expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full-length N-terminal GST-tagged SAPK2a expressed in baculovirus infected Sf21 insect cells using MBP as substrate Inhibition of human full-length N-terminal GST-tagged SAPK2a expressed in baculovirus infected Sf21 insect cells using MBP as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full-length N-terminal GST-tagged SAPK2b2 expressed in baculovirus infected Sf21 insect cells using MBP as substrate Inhibition of human full-length N-terminal GST-tagged SAPK2b2 expressed in baculovirus infected Sf21 insect cells using MBP as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full-length N-terminal His6-tagged Fyn expressed in baculovirus infected Sf21 insect cells using Src peptide as substrate Inhibition of human full-length N-terminal His6-tagged Fyn expressed in baculovirus infected Sf21 insect cells using Src peptide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full-length N-terminal His6-tagged PKBalpha expressed in baculovirus infected Sf21 insect cells using Crosstide as substrate Inhibition of human full-length N-terminal His6-tagged PKBalpha expressed in baculovirus infected Sf21 insect cells using Crosstide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full-length N-terminal His6-tagged PKCalpha expressed in baculovirus infected Sf21 insect cells using Histone H1 as substrate Inhibition of human full-length N-terminal His6-tagged PKCalpha expressed in baculovirus infected Sf21 insect cells using Histone H1 as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full-length N-terminal His6-tagged PKCgamma expressed in baculovirus infected Sf21 insect cells using Histone H1 as substrate Inhibition of human full-length N-terminal His6-tagged PKCgamma expressed in baculovirus infected Sf21 insect cells using Histone H1 as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full-length N-terminal His-tagged p70S6K expressed in baculovirus infected Sf21 insect cells using CKRRRLASLR as substrate Inhibition of human full-length N-terminal His-tagged p70S6K expressed in baculovirus infected Sf21 insect cells using CKRRRLASLR as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal GST-tagged c-kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate Inhibition of human N-terminal GST-tagged c-kit (544 to end residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal GST-tagged EGFR (696 to end residues) expressed in baculovirus infected Sf21 insect cells using Angiotensin II peptide as substrate Inhibition of human N-terminal GST-tagged EGFR (696 to end residues) expressed in baculovirus infected Sf21 insect cells using Angiotensin II peptide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal GST-tagged FGFR1 (456 to 765 residues) expressed in baculovirus infected Sf21 insect cells using IGF-IRtide (12-527) as substrate Inhibition of human N-terminal GST-tagged FGFR1 (456 to 765 residues) expressed in baculovirus infected Sf21 insect cells using IGF-IRtide (12-527) as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal GST-tagged Flt1 (783 to end residues) expressed in baculovirus infected Sf21 insect cells using KKKSPGEYVNIEFG as substrate Inhibition of human N-terminal GST-tagged Flt1 (783 to end residues) expressed in baculovirus infected Sf21 insect cells using KKKSPGEYVNIEFG as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal GST-tagged Flt3 (564 to end residues) expressed in baculovirus infected Sf21 insect cells using Abltide as substrate Inhibition of human N-terminal GST-tagged Flt3 (564 to end residues) expressed in baculovirus infected Sf21 insect cells using Abltide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal GST-tagged SGK1 (61 to 431 residues) expressed in baculovirus infected Sf21 insect cells Akt/SGK peptide as substrate Inhibition of human N-terminal GST-tagged SGK1 (61 to 431 residues) expressed in baculovirus infected Sf21 insect cells Akt/SGK peptide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged (11 to 552 residues) ROCK2 expressed in baculovirus infected Sf21 insect cells using Long S6 Kinase as substrate Inhibition of human N-terminal His6-tagged (11 to 552 residues) ROCK2 expressed in baculovirus infected Sf21 insect cells using Long S6 Kinase as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged (2 to end residues) PKCbeta expressed in baculovirus infected Sf21 insect cells using Histone H1 as substrate Inhibition of human N-terminal His6-tagged (2 to end residues) PKCbeta expressed in baculovirus infected Sf21 insect cells using Histone H1 as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged FGFR3 (447 to 761 residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate Inhibition of human N-terminal His6-tagged FGFR3 (447 to 761 residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged GSK3beta H350L mutant expressed in baculovirus infected Sf21 insect cells using phosphoglycogen synthase peptide-2 as substrate Inhibition of human N-terminal His6-tagged GSK3beta H350L mutant expressed in baculovirus infected Sf21 insect cells using phosphoglycogen synthase peptide-2 as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged IGF1R (959 to end residues) expressed in baculovirus infected Sf21 insect cells Inhibition of human N-terminal His6-tagged IGF1R (959 to end residues) expressed in baculovirus infected Sf21 insect cells	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged insulin receptor (1005 to 1310 residues) expressed in baculovirus infected Sf21 insect cells Inhibition of human N-terminal His6-tagged insulin receptor (1005 to 1310 residues) expressed in baculovirus infected Sf21 insect cells	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged MET (974 to end residues) expressed in baculovirus infected Sf21 insect cells using KKKSPGEYVNIEFG as substrate Inhibition of human N-terminal His6-tagged MET (974 to end residues) expressed in baculovirus infected Sf21 insect cells using KKKSPGEYVNIEFG as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged MSK1 (2 to end residues) expressed in baculovirus infected Sf21 insect cells using Crosstide as substrate Inhibition of human N-terminal His6-tagged MSK1 (2 to end residues) expressed in baculovirus infected Sf21 insect cells using Crosstide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged PDGFRalpha (550 to end residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate Inhibition of human N-terminal His6-tagged PDGFRalpha (550 to end residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged PDGFRbeta (557 to end residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate Inhibition of human N-terminal His6-tagged PDGFRbeta (557 to end residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged PDK1 (52 to end residues) expressed in baculovirus infected Sf21 insect cells using PDKtide as substrate Inhibition of human N-terminal His6-tagged PDK1 (52 to end residues) expressed in baculovirus infected Sf21 insect cells using PDKtide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged PLK1 expressed in baculovirus infected Sf21 insect cells Inhibition of human N-terminal His6-tagged PLK1 expressed in baculovirus infected Sf21 insect cells	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged SYK expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate Inhibition of human N-terminal His6-tagged SYK expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His6-tagged TIE2 (771 to end residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate Inhibition of human N-terminal His6-tagged TIE2 (771 to end residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu4-Tyr) (4:1) as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His-tagged JNK1alpha1 expressed in baculovirus infected Sf21 insect cells using ATF2 as substrate Inhibition of human N-terminal His-tagged JNK1alpha1 expressed in baculovirus infected Sf21 insect cells using ATF2 as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal His-tagged KDR (790 to end residues) expressed in baculovirus infected Sf21 insect cells using myelin basic protein as substrate Inhibition of human N-terminal His-tagged KDR (790 to end residues) expressed in baculovirus infected Sf21 insect cells using myelin basic protein as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of recombinant full-length human N-terminal GST-tagged CDK1/cyclinB expressed in baculovirus infected Sf21 insect cells using Abltide as substrate Inhibition of recombinant full-length human N-terminal GST-tagged CDK1/cyclinB expressed in baculovirus infected Sf21 insect cells using Abltide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of recombinant full-length human N-terminal His6-tagged AuroraA expressed in baculovirus infected Sf21 insect cells using Kemptide as substrate Inhibition of recombinant full-length human N-terminal His6-tagged AuroraA expressed in baculovirus infected Sf21 insect cells using Kemptide as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of recombinant human N-terminal His6-tagged Abl (27 to end residues) expressed in baculovirus infected Sf21 insect cells using Abltide as substrate Inhibition of recombinant human N-terminal His6-tagged Abl (27 to end residues) expressed in baculovirus infected Sf21 insect cells using Abltide as substrate	[PMID: 30755337]
Sf21	IC₅₀	261 nM Compound: JTE-952; (S)-8b	Inhibition of recombinant human N-terminal His6-tagged TrkA (440 to end residues) expressed in baculovirus infected Sf21 insect cells using KKKSPGEYVNIEFG as substrate Inhibition of recombinant human N-terminal His6-tagged TrkA (440 to end residues) expressed in baculovirus infected Sf21 insect cells using KKKSPGEYVNIEFG as substrate	[PMID: 30755337]
Sf21	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of full-length human N-terminal His-tagged JNK2alpha2 expressed in baculovirus infected Sf21 insect cells using ATF2 as substrate Inhibition of full-length human N-terminal His-tagged JNK2alpha2 expressed in baculovirus infected Sf21 insect cells using ATF2 as substrate	[PMID: 30755337]
Sf9	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human full-length N-terminal His-tagged SRC expressed in baculovirus infected Sf9 insect cells using Poly-(Glu4:Tyr) as substrate measured after 35 mins Inhibition of human full-length N-terminal His-tagged SRC expressed in baculovirus infected Sf9 insect cells using Poly-(Glu4:Tyr) as substrate measured after 35 mins	[PMID: 30755337]
Sf9	IC₅₀	>1000 nM Compound: JTE-952; (S)-8b	Inhibition of human N-terminal GST-tagged c-RAF Y340D/Y341D double mutant (306 to 648 residues) expressed in baculovirus infected Sf9 insect cells using MEK1(K97R) as substrate measured after 1 hr Inhibition of human N-terminal GST-tagged c-RAF Y340D/Y341D double mutant (306 to 648 residues) expressed in baculovirus infected Sf9 insect cells using MEK1(K97R) as substrate measured after 1 hr	[PMID: 30755337]

In Vivo

JTE-952 (3 mg/kg, p.o. once-daily) treatment reduces the overall progression of the clinical score, including inflammation and bone erosion in mouse model of collagen-induced arthritis (CIA model)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Mouse model of collagen-induced arthritis (CIA model)^[1].
Dosage:

3 mg/kg.
Administration:

Oral once-daily.
Result:

Reduced the overall progression of the clinical score, including inflammation and bone erosion.

Chemical Information

CAS. Nr. 1255303-54-8
Appearance Solid
Molecular Weight 518.60
Formel C₃₀H₃₄N₂O₆
Color White to off-white
SMILES

O=C(N1CC(C2=CC=C(OCC3=CC=C(C4CC4)C=C3)C(OC)=C2)C1)C5=NC=CC(COC[C@@H](O)CO)=C5
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 100 mg/mL (192.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.9283 mL

9.6413 mL

19.2827 mL

5 mM

0.3857 mL

1.9283 mL

3.8565 mL

10 mM

0.1928 mL

0.9641 mL

1.9283 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Ikegashira K, et al. Optimization of an azetidine series as inhibitors of colony stimulating factor-1 receptor (CSF-1R) Type II to lead to the clinical candidate JTE-952. Bioorg Med Chem Lett. 2019 Apr 1;29(7):873-877. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.9283 mL	9.6413 mL	19.2827 mL	48.2067 mL
	5 mM	0.3857 mL	1.9283 mL	3.8565 mL	9.6413 mL
	10 mM	0.1928 mL	0.9641 mL	1.9283 mL	4.8207 mL
	15 mM	0.1286 mL	0.6428 mL	1.2855 mL	3.2138 mL
	20 mM	0.0964 mL	0.4821 mL	0.9641 mL	2.4103 mL
	25 mM	0.0771 mL	0.3857 mL	0.7713 mL	1.9283 mL
	30 mM	0.0643 mL	0.3214 mL	0.6428 mL	1.6069 mL
	40 mM	0.0482 mL	0.2410 mL	0.4821 mL	1.2052 mL
	50 mM	0.0386 mL	0.1928 mL	0.3857 mL	0.9641 mL
	60 mM	0.0321 mL	0.1607 mL	0.3214 mL	0.8034 mL
	80 mM	0.0241 mL	0.1205 mL	0.2410 mL	0.6026 mL
	100 mM	0.0193 mL	0.0964 mL	0.1928 mL	0.4821 mL

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JTE-952

Immunology/Inflammation Compound Library

Kinase Inhibitor Library

Protein Tyrosine Kinase Compound Library

Coagulation and Anti-coagulation Compound Library

Pain-Related Compound Library

Membrane Protein-targeted Compound Library

Highly Selective Inhibitors Library

Cytokine Inhibitors Library

Macrophage Related Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Anti-Brain Cancer Compound Library

Protein Kinase Compound Library

Cell Proliferation Compound Library

High-Throughput Bioactive Compound Library

Posttranslational Modification Library

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

JTE-952

Immunology/Inflammation Compound Library

Kinase Inhibitor Library

Protein Tyrosine Kinase Compound Library

Coagulation and Anti-coagulation Compound Library

Pain-Related Compound Library

Membrane Protein-targeted Compound Library

Highly Selective Inhibitors Library

Cytokine Inhibitors Library

Macrophage Related Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Anti-Brain Cancer Compound Library

Protein Kinase Compound Library

Cell Proliferation Compound Library

High-Throughput Bioactive Compound Library

Posttranslational Modification Library

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

JTE-952 Related Classifications

HY-122906 Related Classifications