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Art. -Nr.: HY-185347

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AChE-IN-114

AChE-IN-114 is a selective AChE inhibitor and shows weak inhibitory activity for BChE. AChE-IN-114 can be used for the research of alzheimer’s disease.

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CAS. Nr.: 2365405-51-0
Formel: C₁₈H₁₂Cl₂O₃
Molecular Weight:347.19

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

AChE-IN-114 Chemical Structure

CAS. Nr.: 2365405-51-0

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

AChE-IN-114 is a selective AChE inhibitor and shows weak inhibitory activity for BChE. AChE-IN-114 can be used for the research of alzheimer’s disease^[1].

IC₅₀ & Target^[1]

AChE

BChE

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen :

AChE
BChE

In Vitro

AChE-IN-114 (Compound 2v) (10 μM) acts as a mixed type inhibitor of electric eel acetylcholinesterase with a K_i of 12.19-21.46 μM, shows minimal butyrylcholinesterase inhibition, and is non-cytotoxic to multiple human tumor and non-malignant mouse fibroblast cell lines with an EC₅₀ >30 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2365405-51-0
Molecular Weight 347.19
Formel C₁₈H₁₂Cl₂O₃
SMILES

O=C(OC(/C=C/C1=CC=CC=C1Cl)=O)/C=C/C2=CC=CC(Cl)=C2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Gießel JM, et al. Substituted cinnamic anhydrides act as selective inhibitors of acetylcholinesterase. Bioorg Chem. 2019;90:103058. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
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AChE-IN-114

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

AChE-IN-114 Related Classifications

HY-185347 Related Classifications