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Art. -Nr.: HY-113091

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DL-α-Tocotrienol

Alpha-Tocotrienol is a vitamin E analog with anti-apoptotic neuroprotective action and antioxidant properties. Alpha-Tocotrienol prevents oxidative stress-independent apoptotic cell death, DNA cleavage, and nuclear morphological changes.

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CAS. Nr.: 1721-51-3
Formel: C₂₉H₄₄O₂
Molecular Weight:424.66

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

DL-α-Tocotrienol Chemical Structure

CAS. Nr.: 1721-51-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	110 μM Compound: d,l-alpha-tocotrienol	Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 6 (h) Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 6 (h)	[PMID: 1433170]
HepG2	IC₅₀	380 μM Compound: d,l-alpha-tocotrienol	Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 2 (h) Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 2 (h)	[PMID: 1433170]
HepG2	IC₅₀	94 μM Compound: d,l-alpha-tocotrienol	Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 4 (h) Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 4 (h)	[PMID: 1433170]

Chemical Information

CAS. Nr. 1721-51-3
Molecular Weight 424.66
Formel C₂₉H₄₄O₂
SMILES

OC1=C(C)C(C)=C2C(CCC(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)(C)O2)=C1C
Structure Classification
- Phenols
- Monophenols
Initial Source
- Animals
- Endogenous metabolite
human blood
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Fumitaka Osakada, et al. Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacology. 2004 Nov;47(6):904-15. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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