Antitrypanosomal agent 19
Antitrypanosomal agent 19 (compound 10) is an orally available antitrypanosomal agent. Antitrypanosomal agent 19 effectively inhibits the growth of trypanosomatids T. b. brucei, T. b. gambiense and T. b. rhodesiense, mitigating the Human trypanosomiasis (HAT)-induced acute infectious toxicity in mice.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C10H11N3O4S
- Molecular Weight:269.28
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Trypanosome[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
>75 μM
Compound: 10
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Cytotoxicity against human HepG2 cells assessed as cell growth measured after 72 hrs mby MTT assay
Cytotoxicity against human HepG2 cells assessed as cell growth measured after 72 hrs mby MTT assay
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[PMID: 37984297] |
Chemical Information
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Molecular Weight 269.28
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Formel C10H11N3O4S
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SMILES
O=C(C1=CC=C([N+]([O-])=O)S1)NC/C=C/C(NC)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Antitrypanosomal agent 19 Related Classifications
HY-163003 Related Classifications
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