Antitubercular agent-29
Antitubercular agent-29 (compound 6xa) is a potent agent resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor with MIC of 0.03 μg/mL against agent-susceptible (DS)-Mtb strains, MIC of 0.03-0.06 μg/mL against DR-Mtb strains, and favourable selectivity (SI>40) against Vero cells.
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- Formel: C20H12ClN3O5
- Molecular Weight:409.78
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
MIC: 0.03 µg/mL in DS-Mtb, 0.03-0.06 µg/mL in DR-Mtb[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | CC50 |
5 μg/mL
Compound: 6xa
|
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
|
[PMID: 35487101] |
Chemical Information
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Molecular Weight 409.78
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Formel C20H12ClN3O5
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SMILES
O=C(C1=CC=C(NC2=NC3=CC(Cl)=CC=C3O2)C=C1)/C=C/C4=CC=C([N+]([O-])=O)O4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)