Antitumor agent-149
Antitumor agent-149 (Compound 3) is an analogue of Echinomycin (HY-106101). Antitumor agent-149 inhibits HIF-1α-mediated transcription. Antitumor agent-149 induces cancer cell apoptosis. Antitumor agent-149 inhibits tumor growth in SW620 xenograft mice model.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2368983-54-2
- Formel: C52H64N10O14S
- Molecular Weight:1085.19
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
Antitumor agent-149 shows cytotoxicity against SW620 and MIA PaCa-2 cells with IC50s of 0.85 nM and 1.4 nM respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2368983-54-2
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Molecular Weight 1085.19
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Formel C52H64N10O14S
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SMILES
O=C(N[C@@H](C(N[C@H](C(N([C@@H](CSC1)C(N([C@H]2C(C)C)C)=O)C)=O)C)=O)COC([C@H](C(C)C)N(C([C@H]1N(C([C@H](C)NC([C@H](NC(C3=NC(C=CC=C4)=C4C=C3O)=O)COC2=O)=O)=O)C)=O)C)=O)C5=NC(C=CC=C6)=C6C=C5O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Antitumor agent-149 Related Classifications
HY-161425 Related Classifications
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