Asulam
Based on 1 publication(s) in Google Scholar
Asulam is a sulfonamide Herbicide, Antibacterial agent, and DHPS inhibitor. Asulam targets the folate biosynthesis pathway. Asulam inhibits photosynthesis and ATP production, while inducing alterations in amino acid metabolism, mitotic spindle disruption leading to metaphase arrest, and chromosome aberration induction. Asulam impedes the growth of transformed root species. Asulam has activity against Arabidopsis thaliana and Escherichia coli.
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- Reinheit : 99.90%
- CAS. Nr.: 3337-71-1
- Formel: C8H10N2O4S
- Molecular Weight:230.24
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
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- Reinheit & Dokumentation
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Publications Citing Use of MedChemExpress (MCE) Asulam
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Biologische Aktivität
Beschreibung
In Vitro
Asulam (0.125-4 mM; 15 days) is the most effective of the tested sulfonamide herbicides against Arabidopsis thaliana, inhibiting growth from 0.25 mM onward after pre-emergence application[1].
Asulam (100 μg/mL) selects for Sulfamethoxazole (HY-B0322)-tolerant Escherichia coli BW25113 in vitro by increasing the frequency of chromosomal folP mutations[3].
Asulam (1.1 kg ae/ha; 6 days) does not significantly affect the chlorophyll content of wild oat (Avena fatua L.) leaves 6 days after foliar application at 1.1 kg/ha[4].
Asulam (1.1 kg ae/ha; 6 days) inhibits ATP production by 35% in wild oat (Avena fatua L.) leaves 6 days after foliar application of 1.1 kg/ha[4].
Asulam inhibits the growth of Cirsium cell suspension cultures but does not cause a significant loss of cell viability as determined by fluorescein diacetate staining[5].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 3337-71-1
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Appearance Powder
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Molecular Weight 230.24
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Formel C8H10N2O4S
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Color Off-white to light brown
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SMILES
O=C(NS(=O)(C1=CC=C(C=C1)N)=O)OC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 50 mg/mL (217.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Reinheit & Dokumentation
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Data Sheet (277 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3433 mL | 21.7165 mL | 43.4329 mL | 108.5823 mL |
| 5 mM | 0.8687 mL | 4.3433 mL | 8.6866 mL | 21.7165 mL | |
| 10 mM | 0.4343 mL | 2.1716 mL | 4.3433 mL | 10.8582 mL | |
| 15 mM | 0.2896 mL | 1.4478 mL | 2.8955 mL | 7.2388 mL | |
| 20 mM | 0.2172 mL | 1.0858 mL | 2.1716 mL | 5.4291 mL | |
| 25 mM | 0.1737 mL | 0.8687 mL | 1.7373 mL | 4.3433 mL | |
| 30 mM | 0.1448 mL | 0.7239 mL | 1.4478 mL | 3.6194 mL | |
| 40 mM | 0.1086 mL | 0.5429 mL | 1.0858 mL | 2.7146 mL | |
| 50 mM | 0.0869 mL | 0.4343 mL | 0.8687 mL | 2.1716 mL | |
| 60 mM | 0.0724 mL | 0.3619 mL | 0.7239 mL | 1.8097 mL | |
| 80 mM | 0.0543 mL | 0.2715 mL | 0.5429 mL | 1.3573 mL | |
| 100 mM | 0.0434 mL | 0.2172 mL | 0.4343 mL | 1.0858 mL |
Asulam Related Classifications
HY-B1838 Related Classifications
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