Br-PEG4-OH
Based on 1 Customer Validation
Br-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Reinheit: 98.16%
- CAS. Nr.: 85141-94-2
- Formel: C8H17BrO4
- Molecular Weight:257.12
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 85141-94-2
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Appearance Liquid (Density: 1.350±0.06 g/cm3)
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Molecular Weight 257.12
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Formel C8H17BrO4
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Color Colorless to light yellow
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SMILES
BrCCOCCOCCOCCO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (388.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (265 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8892 mL | 19.4462 mL | 38.8923 mL | 97.2309 mL |
| 5 mM | 0.7778 mL | 3.8892 mL | 7.7785 mL | 19.4462 mL | |
| 10 mM | 0.3889 mL | 1.9446 mL | 3.8892 mL | 9.7231 mL | |
| 15 mM | 0.2593 mL | 1.2964 mL | 2.5928 mL | 6.4821 mL | |
| 20 mM | 0.1945 mL | 0.9723 mL | 1.9446 mL | 4.8615 mL | |
| 25 mM | 0.1556 mL | 0.7778 mL | 1.5557 mL | 3.8892 mL | |
| 30 mM | 0.1296 mL | 0.6482 mL | 1.2964 mL | 3.2410 mL | |
| 40 mM | 0.0972 mL | 0.4862 mL | 0.9723 mL | 2.4308 mL | |
| 50 mM | 0.0778 mL | 0.3889 mL | 0.7778 mL | 1.9446 mL | |
| 60 mM | 0.0648 mL | 0.3241 mL | 0.6482 mL | 1.6205 mL | |
| 80 mM | 0.0486 mL | 0.2431 mL | 0.4862 mL | 1.2154 mL | |
| 100 mM | 0.0389 mL | 0.1945 mL | 0.3889 mL | 0.9723 mL |