Bromo-PEG2-bromide
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Bromo-PEG2-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- Reinheit: 98.25%
- CAS. Nr.: 31255-10-4
- Formel: C6H12Br2O2
- Molecular Weight:275.97
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 31255-10-4
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Appearance Liquid (Density: 1.6777 g/cm3)
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Molecular Weight 275.97
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Formel C6H12Br2O2
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Color Colorless to light yellow
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SMILES
BrCCOCCOCCBr
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (362.36 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6236 mL | 18.1179 mL | 36.2358 mL | 90.5896 mL |
| 5 mM | 0.7247 mL | 3.6236 mL | 7.2472 mL | 18.1179 mL | |
| 10 mM | 0.3624 mL | 1.8118 mL | 3.6236 mL | 9.0590 mL | |
| 15 mM | 0.2416 mL | 1.2079 mL | 2.4157 mL | 6.0393 mL | |
| 20 mM | 0.1812 mL | 0.9059 mL | 1.8118 mL | 4.5295 mL | |
| 25 mM | 0.1449 mL | 0.7247 mL | 1.4494 mL | 3.6236 mL | |
| 30 mM | 0.1208 mL | 0.6039 mL | 1.2079 mL | 3.0197 mL | |
| 40 mM | 0.0906 mL | 0.4529 mL | 0.9059 mL | 2.2647 mL | |
| 50 mM | 0.0725 mL | 0.3624 mL | 0.7247 mL | 1.8118 mL | |
| 60 mM | 0.0604 mL | 0.3020 mL | 0.6039 mL | 1.5098 mL | |
| 80 mM | 0.0453 mL | 0.2265 mL | 0.4529 mL | 1.1324 mL | |
| 100 mM | 0.0362 mL | 0.1812 mL | 0.3624 mL | 0.9059 mL |
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