Carbiphene
Carbiphene is a GABAA receptor allosteric modulator. Carbiphene inhibits [35S] TBPS binding and enhances [3H] muscimol binding on rat forebrain membranes, acting on specific GABAA receptor subsets. Carbiphene can be used in research related to schizophrenia.
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- CAS. Nr.: 15687-16-8
- Formel: C28H34N2O2
- Molecular Weight:430.59
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Carbiphene inhibits the binding of [35S]TBPS to rat whole forebrain membranes with an IC50 of 12 μM[1].
Carbiphene enhances the binding of [3H]MUS to rat whole forebrain membranes, with an EC50 of 34 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 15687-16-8
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Molecular Weight 430.59
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Formel C28H34N2O2
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SMILES
O=C(N(C)CCN(C)CCC=1C=CC=CC1)C(OCC)(C=2C=CC=CC2)C=3C=CC=CC3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Squires RF, et al. Additivities of compounds that increase the numbers of high affinity [3H]muscimol binding sites by different amounts define more than 9 GABA(A) receptor complexes in rat forebrain: implications for schizophrenia and clozapine research. Neurochem Res. 2000;25(12):1587-1601. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Carbiphene Related Classifications
HY-105567 Related Classifications
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