1616632-77-9

Dordaviprone Chemical Structure
1616632-77-9

Chemical Structure

Dordaviprone

Synonym(s): TIC10; ONC-201

  • CAS. Nr.: 1616632-77-9
  • Formula:C24H26N4O
  • Molecular Weight:386.49

IUPAC Name: 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one

InChIKey: VLULRUCCHYVXOH-UHFFFAOYSA-N

SMILES: O=C1N(CC2=CC=CC=C2C)C3=NCCN3C4=C1CN(CC5=CC=CC=C5)CC4

Biological Activity: Dordaviprone (TIC10) is a potent, orally active, and stable tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) inducer which acts by inhibiting Akt and ERK, consequently activating Foxo3a and significantly inducing cell surface TRAIL. Dordaviprone can cross the blood-brain barrier[1].

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-15615A 		Dordaviprone 99.90% Dordaviprone (TIC10) is a potent, orally active, and stable tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) inducer which acts by inhibiting Akt and ERK, consequently activating Foxo3a and significantly inducing cell surface TRAIL. Dordaviprone can cross the blood-brain barrier.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References

Keywords