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Cat. No.: HY-168062

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ZYZ-17

ZYZ-17 is an activator of human caseinolytic peptidase P ( hClpP), with an EC₅₀ value of 0.24 μM. ZYZ-17 can be used in anticancer research.

For research use only. We do not sell to patients.

CAS No.: 3065246-14-9
Formula: C₂₅H₂₄F₄N₄O
Molecular Weight:472.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

ZYZ-17 Chemical Structure

CAS No.: 3065246-14-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

ZYZ-17 is an activator of human caseinolytic peptidase P ( hClpP), with an EC₅₀ value of 0.24 μM. ZYZ-17 can be used in anticancer research^[1].

IC₅₀ & Target

hClpP

0.24 μM (EC₅₀)

Chemical Information

CAS No. 3065246-14-9
Molecular Weight 472.48
Formula C₂₅H₂₄F₄N₄O
SMILES

O=C1N(CC2=CC=C(C(F)(F)F)C=C2)C3=NCCCN3C4=C1CN(CC4)CC5=CC(F)=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang Y, et al. Development of novel imipridone derivatives with potent anti-cancer activities as human caseinolytic peptidase P (hClpP) activators. Bioorg Chem. 2024 Aug 30;153:107765. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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