CDr20
CDr20 is a fluorescent chemical probe capable of crossing the blood-brain barrier. CDr20 undergoes glucuronidation catalyzed by the UDP-glucuronosyltransferase Ugt1a7c, which triggers a fluorescence turn-on response. CDr20 enables visualization of live microglial cells. CDr20 can be used for research on Alzheimer's disease, stroke, and autism.
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- CAS. Nr.: 1201643-01-7
- Formel: C19H17BF2N2O2
- Molecular Weight:354.16
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
In Vitro
CDr20 specifically labels mouse primary microglia in mixed glial cultures, with 97.3% colocalization with the microglial marker Iba-1, and minimal to no labeling of astrocytes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1201643-01-7
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Molecular Weight 354.16
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Formel C19H17BF2N2O2
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SMILES
[F-][B+3]1([N]2=CC=CC2=CC3=C(C)C=C([N-]31)/C=C/C4=CC=C(C(O)=C4)OC)[F-]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CDr20 Related Classifications
HY-D3180 Related Classifications
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