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Art. -Nr.: HY-N15662

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Coumestan

Coumestan is a secondary metabolite found in leguminous plants and can be used as drug intermediate Coumestan can be used to synthesize various coumarin compounds such as Coumestrol (HY-N2335), Glytabastan B, and Coumestan Pks13 inhibitor. Coumestans can be used for the study of anti-cancer, anti-inflammatory, anti-oxidative, antibacterial, neuroprotective and organ protective.

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CAS. Nr.: 479-12-9
Formel: C₁₅H₈O₃
Molecular Weight:236.22

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Coumestan Chemical Structure

CAS. Nr.: 479-12-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

Chemical Information

CAS. Nr. 479-12-9
Molecular Weight 236.22
Formel C₁₅H₈O₃
SMILES

O=C1C2=C(C3=C(O1)C=CC=C3)OC4=C2C=CC=C4
Structure Classification
- Phenylpropanoids
- Coumarins
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Tabbasum MT, R S. Emerging Coumestans in Cancer Therapy With Mechanistic Insights and Clinical Potential. Arch Pharm (Weinheim). 2025 Jul;358(7):e70058. doi: 10.1002/ardp.70058. [Content Brief]

[2]. Kim JE, et al. Coumestrol Epigenetically Suppresses Cancer Cell Proliferation: Coumestrol Is a Natural Haspin Kinase Inhibitor. Int J Mol Sci. 2017 Oct 24;18(10):2228. [Content Brief]

[3]. Lun S, et al. Therapeutic potential of coumestan Pks13 inhibitors for tuberculosis. Antimicrob Agents Chemother. 2023 May 1;95(5):e02190-20. [Content Brief]

[4]. Seong SH, et al. Phytoestrogen Coumestrol Selectively Inhibits Monoamine Oxidase-A and Amyloid β Self-Aggregation. Nutrients. 2022 Sep 16;14(18):3822. [Content Brief]

[5]. Djafarou S, Boulebd H. The radical scavenger capacity and mechanism of prenylated coumestan-type compounds: a DFT analysis. Free Radic Res. 2022 Mar-Apr;56(3-4):273-281. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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