Cyclo(CRVIIF)
Cyclo CRVIIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains KD of 65 and 123 μM, respectively.
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- Formel: C35H57N9O6S
- Molecular Weight:731.95
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
|
HIF-1α 65 μM (Kd) |
HIF-2α 123 μM (Kd) |
Chemical Information
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Molecular Weight 731.95
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Formel C35H57N9O6S
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Sequence
Cyclo(Cys-Arg-Val-Ile-Ile-Phe)
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Sequence Shortening
Cyclo(CRVIIF)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)