DAPK1-binding peptide
DAPK1-binding peptide is a peptide derived from GluN2B that selectively recognizes the activated, dephosphorylated DAPK1 kinase. DAPK1-binding peptide can serve as the binder moiety of PVtCD-cTP-AlkF-2 (HY-188196).
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- CAS. Nr.: 1432595-61-3
- Formel: C73H126N30O19
- Molecular Weight:1727.97
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
DAPK1 |
In Vitro
DAPK1-binding peptide can form a stable ternary complex PVtCD-cTP-AlkF-2 (HY-188196) together with DAPK1 protein and VHL E3 ubiquitin ligase ligand, and PVtCD-cTP-AlkF-2 is a ROS-responsive DAPK1 BmTAC activator[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1432595-61-3
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Molecular Weight 1727.97
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Formel C73H126N30O19
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SMILES
N[C@@H](CCCCN)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC1=CC=C(O)C=C1)=O)CO)=O)CC2=CNC=N2)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC(C)C)=O)CCCCN)=O)CC(N)=O)=O)CCCNC(N)=N)=O)CC(N)=O)=O)CCCCN)=O
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Sequence
Lys-Lys-Asn-Arg-Asn-Lys-Leu-Arg-Arg-Gln-His-Ser-Tyr
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Sequence Shortening
KKNRNKLRRQHSY
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)