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Art. -Nr.: HY-114621B

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DB772 free base

Name: DB772 free base
Brand: MedChemExpress
SKU: HY-114621B
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1 Cited Publications

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Based on 1 publication(s) in Google Scholar

DB772 free base is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 free base also has anti-prion activity.

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CAS. Nr.: 433735-90-1
Formel: C₂₀H₁₆N₄O
Molecular Weight:328.37

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

DB772 free base Chemical Structure

CAS. Nr.: 433735-90-1

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Biologische Aktivität

Beschreibung

DB772 free base is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 free base also has anti-prion activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
B16	IC₅₀	8.6 μM Compound: DB772	Drug concentration required to inhibit B16 cell growth by 50% after 72 hours of incubation Drug concentration required to inhibit B16 cell growth by 50% after 72 hours of incubation	[PMID: 11985467]

Chemical Information

CAS. Nr. 433735-90-1
Molecular Weight 328.37
Formel C₂₀H₁₆N₄O
SMILES

C1(N=C(C2=CC=C(C3=CC=C(C4=NCCN4)C=C3)O2)N5)=C5C=CC=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

J Vet Med Sci

Improved method for elimination of bovine viral diarrhea virus from contaminated cell lines using virus inhibitor DB772. [Abstract]

2025 Aug 1. PMID: 40754431

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. James B Stanton, et al. Discovery of a novel, monocationic, small-molecule inhibitor of scrapie prion accumulation in cultured sheep microglia and Rov cells. PLoS One. 2012;7(11):e51173. [Content Brief]

[2]. Benjamin W Newcomer, et al. Efficacy of an antiviral compound to inhibit replication of multiple pestivirus species. Antiviral Res. 2012 Nov;96(2):127-9. [Content Brief]

[3]. Kelcey D Dinkel, et al. Antiprion Activity of DB772 and Related Monothiophene- and Furan-Based Analogs in a Persistently Infected Ovine Microglia Culture System. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5467-82. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

DB772 free base

1 Cited Publications

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DB772 free base

Publications Citing Use of MedChemExpress (MCE) DB772 free base

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Chemical Information

Publications (1)

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DB772 free base Related Classifications

HY-114621B Related Classifications

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