EXEL-0346
EXEL-0346 is an orally active glucosylceramide synthase (GCS) inhibitor, with an IC50 of 2 nM. EXEL-0346 combined with insulin increases pAkt. EXEL-0346 effectively reduces the levels of Glucosylceramide, Lactosylceramide and GM3. EXEL-0346 improves obesity and diabetes.
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- CAS. Nr.: 1239893-96-9
- Formel: C27H29BrF3N3O3
- Molecular Weight:580.44
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
IC50: 2 nM (GCS)[1]
Chemical Information
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CAS. Nr. 1239893-96-9
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Molecular Weight 580.44
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Formel C27H29BrF3N3O3
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SMILES
O=C(C1(C2=CC=C(OC(F)(F)F)C=C2)CC1)N[C@@H](CC3=CC=C(Br)C=C3)C(N4C5CC(N)CC4CC5)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
EXEL-0346 Related Classifications
HY-112488 Related Classifications
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