CGRRF1 - cell growth regulator with ring finger domain 1 Gene

Also Known as CGR19; RNF197

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10668

About CGRRF1

Cytogenetic location: 14q22.2 Genomic coordinates (GRCh38): 14:54,509,906-54,539,292 (from NCBI)

This gene has 11 transcripts (splice variants) and 220 orthologues. Ubiquitous expression in testis (RPKM 10.6), thyroid (RPKM 6.6) and 25 other tissues.

Summary

Predicted to enable metal ion binding activity. Predicted to be involved in negative regulation of cell growth. Located in endoplasmic reticulum and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CGRRF1 Products (1)

mRNA Protein Name
NM_006568.3 NP_006559.1 cell growth regulator with RING finger domain protein 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
27485036 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CGRRF1 Protein Structure

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (271 - 314)

  • 0
  • 100
  • 200
  • 300
  • 332 a.a.
Protein Preferred Names Protein Names

cell growth regulator with RING finger domain protein 1

  • RING finger protein 197

CGRRF1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
CGRRF1 Q99675 JAGN1 Homo sapiens Q8N5M9
Y2H Prey Pooling
32296183
Intra
CGRRF1 Q99675 SLC30A3 Homo sapiens Q99726
Validated Y2H
32296183
Intra
CGRRF1 Q99675 PGAP2 Homo sapiens Q9UHJ9-5
Validated Y2H
32296183
Intra
CGRRF1 Q99675 LNPEP Homo sapiens Q9UIQ6-2
Validated Y2H
32296183
Intra
CGRRF1 Q99675 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra
CGRRF1 Q99675 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra
CGRRF1 Q99675 SUSD3 Homo sapiens Q96L08
Y2H Prey Pooling
32296183
Intra
CGRRF1 Q99675 SUSD3 Homo sapiens Q96L08
Y2H Array
32296183
Intra
CGRRF1 Q99675 MARCHF5 Homo sapiens Q9NX47
Validated Y2H
32296183
Intra
CGRRF1 Q99675 FFAR2 Homo sapiens O15552
Y2H Array
32296183
Intra
CGRRF1 Q99675 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
Intra
CGRRF1 Q99675 TMEM140 Homo sapiens Q9NV12
Validated Y2H
32296183
Intra
CGRRF1 Q99675 MTIF3 Homo sapiens Q9H2K0
Y2H Array
32296183
Intra
CGRRF1 Q99675 MTIF3 Homo sapiens Q9H2K0
Validated Y2H
32296183
Intra
CGRRF1 Q99675 MTIF3 Homo sapiens Q9H2K0
Y2H Prey Pooling
32296183
Intra
CGRRF1 Q99675 KLRC1 Homo sapiens P26715
Y2H Prey Pooling
32296183
Intra
CGRRF1 Q99675 KLRC1 Homo sapiens P26715
Y2H Array
32296183
Intra
CGRRF1 Q99675 RHBDD1 Homo sapiens Q8TEB9
Y2H Prey Pooling
32296183
Intra
CGRRF1 Q99675 RHBDD1 Homo sapiens Q8TEB9
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS02588 CGRRF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CGRRF1 VGNC VGNC:39185
Bos taurus CGRRF1 VGNC VGNC:27260
Rattus norvegicus CGRRF1 RGD RGD:620803
Felis catus CGRRF1 VGNC VGNC:104367
Macaca mulatta CGRRF1 VGNC VGNC:84322
Mus musculus CGRRF1 MGD MGI:1916368
Others CGRRF1 NCBI