Ran - RAN, member RAS oncogene family Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19384

Summary

Predicted to enable several functions, including dynein intermediate chain binding activity; guanyl ribonucleotide binding activity; and importin-alpha family protein binding activity. Predicted to contribute to pre-miRNA binding activity. Acts upstream of or within actin Cytoskeleton organization; protein import into nucleus; and protein-containing complex localization. Located in cytoplasm and nuclear envelope. Is expressed in several structures, including branchial arch; central nervous system; extraembryonic component; hemolymphoid system gland; and sensory organ. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human RAN (RAN, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Ran Products (1)

mRNA Protein Name
NM_009391.3 NP_033417.1 GTP-binding nuclear protein Ran

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
11809816 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
21874009 MGI
acts upstream of or within protein import into nucleus IDA
IDA: Inferred from direct assay
11809816 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
21874009 MGI
acts upstream of or within protein-containing complex localization IMP
IMP: Inferred from mutant phenotype
21874009 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in cytoplasm IDA
IDA: Inferred from direct assay
18347012 MGI
located in nuclear envelope IDA
IDA: Inferred from direct assay
25946333 MGI
located in nucleus IDA
IDA: Inferred from direct assay
18347012 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GTP-binding nuclear protein Ran

  • GTPase Ran

  • ras-like protein TC4

  • ras-related nuclear protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-173350 Ran-IN-1 99.89% Unkown
HY-W250191 Tergitol / Unkown
HY-W141374 CB096 98.72% Unkown
HY-120743 Triplin / Unkown
HY-125964 LLP-3 Inhibitor 98.13% Unkown
HY-RS11641 RAN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16834 Ran Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23276 Ran Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ran NCBI NCBI:5901