Clip1 - CAP-GLY domain containing linker protein 1 Gene

Also Known as Rsn; CLIP-170

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 65201

Summary

Enables microtubule plus-end binding activity. Involved in positive regulation of dendrite development. Located in cytoplasmic microtubule and microtubule plus-end. Orthologous to human CLIP1 (CAP-Gly domain containing linker protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Clip1 Products (4)

mRNA Protein Name
NM_001408966.1 NP_001395895.1 CAP-Gly domain-containing linker protein 1 isoform 2
NM_031745.3 NP_113933.2 CAP-Gly domain-containing linker protein 1 isoform 1
NM_001408966.1 NP_001395895.1 CAP-Gly domain-containing linker protein 1 isoform 2
NM_031745.3 NP_113933.2 CAP-Gly domain-containing linker protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables microtubule binding IDA
IDA: Inferred from direct assay
26972003 RGD
enables microtubule plus-end binding IDA
IDA: Inferred from direct assay
11290329 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11290329 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in positive regulation of dendrite development IMP
IMP: Inferred from mutant phenotype
21430156 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in cytoplasmic microtubule IDA
IDA: Inferred from direct assay
11290329 RGD
located in microtubule plus-end IDA
IDA: Inferred from direct assay
26972003 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CAP-Gly domain-containing linker protein 1

  • cytoplasmic linker protein 170

  • restin (Reed-Steinberg cell-espressed intermediate filament-associated protein)

  • restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)

Clip1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Cross
Clip1 Q9JK25 CSNK2B Homo sapiens P67870
Anti Bait CoIP
20664522
Cross
Clip1 Q9JK25 CLASP1 Homo sapiens Q7Z460
BiFC
11290329
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-171155 CLIP1-LTK fusion protein regulator-1 Inhibitor / Unkown
HY-RS02810 CLIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20887 Clip1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27404 Clip1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clip1 NCBI NCBI:6249